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Home > Natural Products > Lignans (Find 185 items)

Lignans

Rosmarinic Acid

(20283-92-5)
1. Rosmarinic Acid is a phenolic compound with antioxidant and anti-inflammatory activity. Rosmarinic Acid has been shown to inhibit againts peroxidative damage to biomembranes. Rosmarinic Acid also suppresses endotoxin-induced activation of complement and concomitant prostacyclin biosynthesis.
2. An activator of GPR35.

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Honokiol

(35354-74-6)
Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.

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Gomisin A

(58546-54-6)
Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera.IC50 value:Target:in vitro: SolB pretreatment significantly attenuated the increases in alanine aminotransferase and aspartate aminotransferase activity, and prevented elevated hepatic malondialdehyde formation and the depletion of mitochondrial glutathione (GSH) in a dose-dependent manner. SolB also dramatically altered APAP metabolic activation by inhibiting

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ChicoricAcid

(6537-80-0)
Chicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and independent

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magnolin

(31008-18-1)
Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.

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ASARININ

(133-04-0)
(-)-Asarinin is a extract lignan from Zanthoxylum armatum, mainly produced in roots of this herb[1].

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SECOISOLARICIRESINOL

(29388-59-8)
Secoisolariciresinol, isolated from water extract of silver fir (Abies alba) wood, is a lignan, a type of phenylpropanoids.

Methyl rosmarinate

(99353-00-1)
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase[1].
Lignans is a type of natural component formed by the bimolecular polymerization of phenylpropanin. There are four types of monomers that make up lignans: cinnamic acid and occasionally cinnamaldehyde. Cinnamyl alcohol. Acrylic benzene. Allylbenzene. The substance exists in plants and belongs to a phytoestrogen, which has the effect of scavenging free radicals in the body and anti-oxidation.
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