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    Home > Natural Products > Lignans (Find 185 items)

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    Lignans

    Rosmarinic Acid

    (20283-92-5)
    1. Rosmarinic Acid is a phenolic compound with antioxidant and anti-inflammatory activity. Rosmarinic Acid has been shown to inhibit againts peroxidative damage to biomembranes. Rosmarinic Acid also suppresses endotoxin-induced activation of complement and concomitant prostacyclin biosynthesis.
    2. An activator of GPR35.

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    Gomisin A

    (58546-54-6)
    Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera.IC50 value:Target:in vitro: SolB pretreatment significantly attenuated the increases in alanine aminotransferase and aspartate aminotransferase activity, and prevented elevated hepatic malondialdehyde formation and the depletion of mitochondrial glutathione (GSH) in a dose-dependent manner. SolB also dramatically altered APAP metabolic activation by inhibiting

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    ChicoricAcid

    (6537-80-0)
    Chicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and independent

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    magnolin

    (31008-18-1)
    Magnolin, a major component of Magnolia flos (Shin-Yi), inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.

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    Angeloylgomisin O

    (83864-69-1)
    Angeloylgomisin O, a lignin extract of Schisandra rubriflora. Anti-inflammatory properties[1].

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    licarin A

    (51020-86-1)
    Likalin A, also called likalin A, is a kind of lignans in Sanbai herbal medicine. Saururus chinensis, scientific name: Saururuschinensis (LourChemicalbook.) Baill, also known as pond lotus root. The whole plant is used for medicinal purposes, orally used to treat urinary tract infections, urinary tract stones, beriberi edema and nutritional edema; external application to treat carbuncle boils, skin eczema, etc.

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    Angeloylgomisin H

    (66056-22-2)
    Angelica acyl gomixin H has a hepatoprotective effect.

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    gomisin J

    (66280-25-9)
    Gomisin J is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity[1]. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+/calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells. gomisin J has potential benefits in treating nonalcoholic fatty liver disease[2].

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    cleomiscosin A

    (76948-72-6)
    ChEBI: An organic heterotricyclic compound that is 2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one substituted by 4-hydroxy-3-methoxy phenyl group at position 3, a hydroxymethyl group at position 2 and a methoxy group at position 5 (the 2R,3R stereoisomer). It exhibits anti-inflammatory activity.

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    Methyl rosmarinate

    (99353-00-1)
    Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase[1].

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    Lignans is a type of natural component formed by the bimolecular polymerization of phenylpropanin. There are four types of monomers that make up lignans: cinnamic acid and occasionally cinnamaldehyde. Cinnamyl alcohol. Acrylic benzene. Allylbenzene. The substance exists in plants and belongs to a phytoestrogen, which has the effect of scavenging free radicals in the body and anti-oxidation.

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