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Home > Organic Chemistry > Semicarbazides (Find 26 items)

Semicarbazides

Butyl Methacrylate

(97-88-1)
Monomer for resins, solvent coatings, adhesives, oil additives, emulsions for textiles, leather & paper finishing.

THIACETAZONE

(104-06-3)
Thioacetazone (USAN amithiozone) is a synthetic compound discovered during initial work on the sulfonamides, to which it is structurally related. It is only slightly soluble in water. It is a weak bacteristatic drug, with frequent serious side effects, particularly in HIV-positive persons to whom it must never knowingly be given. On the advice of the WHO it no longer has a place in the treatment of tuberculosis, except as a last resort in cases of extreme drug resistance.
In-vitro

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Co102862

(181144-66-1)
Broad spectrum, state-dependent blocker of voltage-gated sodium channels. Displays ~ 80-fold higher affinity for inactivated Na + channels compared to channels in the resting state. Anticonvulsant; displays activity in rodent models of tonic/clonic and partial-complex seizures.

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A-83-01

(909910-43-6)
A 83-01 is a selective inhibitor of TGF-β type I receptor. A 83-01 treatment increases tumor permeability.

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Semicarbazide products (semicarbazides and thiosemicarbazides) have antiviral, anti-infective and antitumor activities by combining with copper or iron in cells. Semicarbazide products are widely used in the preparation of pharmaceuticals, such as furan antibacterials (furazolidone, nitrofurazone, nitrofurantoin) and related compounds.
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