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Is the polarity of estradiol?How to look at the polarity of a compound
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Kaju Deka
Is the polarity of estradiol?How to look at the polarity of a compound
My understanding: In chromatography analysis, it is often said that a certain substance is extremely polar. In fact, it does not mean that the substance molecules are strong, but how many polar groups are there in the substance.If a material molecule has one or more types of hydroxyl, amino, carboxyl, and cymbal groups, we say that the substance is a polar matter, the more polar groups, the stronger the polarity of the substance.The strength of the polarity reflects the retention of the chromatography.For example, the stronger the polarity of the separation material in the anti -phase chromatography, the shorter the peak time may be. The reason is that the non -polar C18 Van Dehua is weak. Of course, this is only one of the factor.
My understanding: In chromatography analysis, it is often said that a certain substance is extremely polar. In fact, it does not mean that the substance molecules are strong, but how many polar groups are there in the substance.If a material molecule has one or more types of hydroxyl, amino, carboxyl, and cymbal groups, we say that the substance is a polar matter, the more polar groups, the stronger the polarity of the substance.The strength of the polarity reflects the retention of the chromatography.For example, the stronger the polarity of the separation material in the anti -phase chromatography, the shorter the peak time may be. The reason is that the non -polar C18 Van Dehua is weak. Of course, this is only one of the factor.
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