Essential mixed cryoglobulinemia vasculitis
Essential mixed cryoglobulinemia (EMC) is also called purpura-arthralgia-cryoglobulinemia syndrome. It is clinically characterized by purpuric skin lesions, arthralgia, anemia, renal damage and hypergammaglobulinemia. Meltzer (1966) first systematically described this disease based on Wintrobe (1933) and Iener (1947). At the same time, it was also found that malignant tumors such as myeloma can also be accompanied by cryoglobulinemia and have the same clinical features as this disease. In addition, diseases such as subacute bacterial endocarditis, leprosy, hemolytic anemia, acute glomerulonephritis, systemic lupus erythematosus, rheumatoid arthritis and Sjögren's syndrome can also be accompanied by cryoglobulinemia, and the cryoglobulinemia associated with these diseases is called secondary cryoglobulinemia.
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Site of disease:
Skin joint blood vessels -
Infectious :
Not contagious -
Frequent population:
This disease can occur in both sexes, but it is more common in women... -
Related symptoms:
Papules Pain Joint pain Dyspigotism Hypocomplementemia -
Concurrent disease:
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