Hepatitis virus-related rheumatic disease refers to chronic active hepatitis caused by hepatitis virus, also known as chronic progressive hepatitis. It is a systemic inflammatory disease caused by immune mechanism and mainly characterized by liver damage. Its characteristics are: ① typical histological changes of liver disease; ② in addition to liver lesions, there are also multi-system damage characteristics; ③ multiple immunological abnormalities. Among the currently known hepatitis virus infections of types A, B, C, D, E, and G, the first five types can be accompanied by chronic extrahepatic tissue and organ damage, but type B (HBV) is the most prominent, followed by type C (HCV), type D (HDV), type A (HAV) and type E (HEV). Hepatitis G virus has not yet been successfully isolated in my country, and no cases have been reported. Saint et al. (1953) first discovered a progressive inflammatory disease with a poor prognosis, with infectious hepatitis as an early manifestation, and named it chronic active hepatitis. Joske (1955) emphasized that the development of viral hepatitis is related to the phenomenon of lupus cells, and proposed that this chronic progressive liver disease should be named lupus-like hepatitis, but it is now completely confirmed that this liver disease is completely different from systemic lupus erythematosus liver disease. Saint et al. (1953) first discovered a progressive inflammatory disease with a poor prognosis, with infectious hepatitis as an early manifestation, and named it chronic active hepatitis. Joske (1955) emphasized that the development of viral hepatitis is related to the phenomenon of lupus cells, and proposed that this chronic progressive liver disease should be named lupus-like hepatitis, but it is now completely confirmed that this liver disease is completely different from systemic lupus erythematosus liver disease.