Congenital spontaneously healing Langerhans' histiocytosis
Congenital Self-Healing Langerhans Histiocytosis (CSLH), also known as Congenital self-healing reticulohistiocytosis, was reported by Hashimoto and Pritzker in 1973, so it is also called Hashimoto-Pritzker disease. It is self-limited and benign, with only skin lesions but no systemic damage. Its skin lesion characteristics and histopathological appearance are actually similar to those of Langerhans cell histiocytosis. Immunohistochemical examination of S-100 protein and CDIa (OKT6) are also positive, and Birbeck granules can also be seen in ultramicroscopic examination. Therefore, some people classify this disease as the most benign type in the spectrum of Langerhans histiocytosis.
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Site of disease:
skin -
Infectious :
Not contagious -
Frequent population:
This disease occurs in infants and newborns -
Related symptoms:
Mucosal damage Histiocytosis Nodules Scabs Enlarged and hard liver -
Concurrent disease:
Related Drugs
Fluorouracil cream
Indication: It is the main chemotherapy drug for malignant hydatidiform mole and choriocarcinoma. It is also used for adjuvant chemotherapy and palliative treatment of breast cancer, digestive tract tumors (including primary and metastatic liver cancer and pancreatic cancer), ovarian cancer and primary bronchial lung cancer. The ointment is used for skin cancer, vulvar leukoplakia, and chest wall metastasis of breast cancer.
Manufacturer:
Beijing Shuangji Pharmaceutical Co., Ltd.
Fluorouracil cream
Indication: It is the main chemotherapy drug for malignant hydatidiform mole and choriocarcinoma. It is also used for adjuvant chemotherapy and palliative treatment of breast cancer, digestive tract tumors (including primary and metastatic liver cancer and pancreatic cancer), ovarian cancer and primary bronchial lung cancer. The ointment is used for skin cancer, vulvar leukoplakia, and chest wall metastasis of breast cancer.
Manufacturer:
Beijing Shuangji Pharmaceutical Co., Ltd.
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