This disease is a disease caused by abnormal iron metabolism, which causes excessive iron content in the body and deposits in various internal organs and produces various symptoms. Clinically, it is divided into two types: spontaneous and secondary. The former is caused by hereditary iron metabolism disorders, characterized by excessive iron absorption, pathological iron deposition, and finally leading to dysfunction of many organs, most notably the liver, pancreas, heart, and pituitary gland. Its typical clinical manifestations are hepatomegaly, diabetes, skin pigmentation, and sexual dysfunction. Some cases may have symptoms such as general weakness, weight loss, abdominal pain, dyspnea, and edema. Secondary hemochromatosis is mostly secondary to long-term repeated massive blood transfusions (such as more than 100 blood transfusions in the treatment of aplastic anemia) and previous iron treatment. It can also be seen in hemolytic diseases, malnutrition, vitamin A deficiency, and long-term diarrhea. In normal people, the total iron content in the body is 3 to 5g. When iron metabolism is impaired, it may accumulate to more than 25g. During blood transfusion, each 1000ml of whole blood contains 500mg of iron. It is generally believed that when the iron intake exceeds 20g, secondary hemochromatosis will occur.