Progressive diaphyseal dysplasia
This disease is also known as Engelmann's disease, diaphyseal sclerosis and camurati-Engelmann-Ribbing disease. It is characterized by symmetrical spindle-shaped enlargement and hardening of the long bone shaft. This disease is rare. Some statistics show that males are slightly more likely to develop the disease than females. The average age of onset is 19.2 years old, ranging from 3 months to 57 years old. The affected long bones are the tibia, femur, fibula, humerus, ulna and radius, and the hand and foot bones are rare. The skull is also a common site of onset.
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