Lip and tongue edema and facial paralysis syndrome
The syndrome of lip and tongue edema and facial paralysis is also known as Melkersson-Rosenthel syndrome. It develops rapidly, with swelling of the face and tongue accompanied by paralysis of the muscles on the lateral side of the swelling. Swelling of the tongue surface or deep longitudinal fissures on the tongue body are often seen, which are characteristic manifestations of this syndrome. This syndrome was first described by Melkersson (1928), and then Rosenthel (1930) found that in addition to swelling of the face and lips accompanied by facial muscle paralysis, there were also longitudinal fissures on the tongue surface, which resembled scrotal skin wrinkles.