Entacapone structure
Entacapone
Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.IC50 Value: 151 nMTarget: COMTin vitro: Entacapone inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapone (< 100 μM) is a potent inhibitor of α-syn and β-amyloid (Aβ) oligomerization and fibrillogenesis, and al
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Shandong Xinhua Pharmaceutical Company Limited
China
China
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API Inactive
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Founded in:
1998-11-20 -
Country:
China -
Address:
Chemical Industry Zone, Zibo High-tech Industrial Development Zone -
Tax NO.:
91370300164103727C -
Registered Funds:
682,407,635 yuan -
Website:
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Email:
F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A.
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ERREGIERRE SPA
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USV LTD
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