It mainly acts on H2 receptors on parietal cells, competitively inhibiting histamine, inhibiting basal gastric acid secretion, and also inhibiting gastric acid secretion stimulated by food, histamine gastrin, caffeine and insulin. After injecting 300mg, it can inhibit basal gastric acid secretion by 80% for 4 to 5 hours, and the effect of inhibiting basal gastric acid by 50% can also be maintained for 4 to 5 hours.

This product is a quinolone antibacterial drug. It has high antibacterial activity against Enterobacteriaceae such as Escherichia coli, Shigella, Klebsiella, Proteus, Enterobacter, etc.; Haemophilus influenzae and Neisseria gonorrhoeae are also highly sensitive to this product; it also has certain antibacterial effects on Pseudomonas such as Acinetobacter and Pseudomonas aeruginosa, Staphylococcus, Pneumococcus, and hemolytic Streptococcus. This product acts on the A subunit of DNA helicase in bacterial cells, inhibiting the synthesis and replication of DNA and exerting a bactericidal effect.

This product is a non-acidic non-steroidal anti-inflammatory drug and a prodrug. It is rapidly metabolized to 6-methoxy-2-naphthylacetic acid (6-MNA) in the liver and has antipyretic, analgesic and anti-inflammatory effects. 1. The anti-inflammatory, analgesic and antipyretic effects are related to the fact that the active metabolites of cabutimetone inhibit the synthesis of prostaglandins in inflammatory tissues; 2. Little effect on gastric mucosa: This product is a non-acidic, non-ionic prodrug, which has no obvious local direct effect on gastric mucosa during absorption; at the same time, this product has little inhibitory effect on the physiological cyclooxygenase of gastric mucosa. Therefore, the incidence of gastrointestinal mucosal erosion and bleeding caused by this product is low; 3. No effect on bleeding and coagulation: This product has no effect on the platelet aggregation induced in vitro in blood samples of healthy volunteers. There are no significant changes in bleeding time and coagulation tests.

Extract from the above information

The pharmacological effects extracted from the above information are not clearly described.