Telmisartan is a specific angiotensin II receptor (ATⅠ type) antagonist. Telmisartan replaces angiotensin II receptors and binds to ATⅠ receptor subtypes with high affinity. It has no agonist effect at any site, selectively binds to ATⅠ receptors, and the binding effect is long-lasting. Telmisartan has no affinity for other receptors (including AT2 and other AT receptors with fewer characteristics). It does not inhibit human plasma renin, nor does it block ion channels, and does not inhibit angiotensin converting enzyme Ⅱ. In humans, 80 mg of telmisartan can almost completely inhibit the increase in blood pressure caused by angiotensin Ⅱ. The inhibitory effect lasts for 24 hours and can still be measured after 48 hours. The antihypertensive effect gradually becomes obvious within 3 hours after the first dose of telmisartan. The maximum antihypertensive effect can be obtained 4 weeks after the start of treatment and can be maintained in long-term treatment. If the treatment is suddenly interrupted, the blood pressure gradually returns to the pre-treatment level after a few days without rebound hypertension. In clinical trials, the incidence of dry cough in the telmisartan treatment group was significantly lower than that in the angiotensin converting enzyme inhibitor treatment group.

Amikacin sulfate is an aminoglycoside antibiotic that has good effects on most Enterobacteriaceae, Pseudomonas aeruginosa, some other Pseudomonas, Acinetobacter, Alcaligenes, etc. It also has good antibacterial effects on meningococci, gonococci, influenza bacilli, Yersinia, Campylobacter fetus, Mycobacterium tuberculosis and some Mycobacterium. Its antibacterial activity is slightly lower than that of gentamicin, but it is stable to the aminoglycoside inactivating enzymes produced by many intestinal Gram-negative bacilli. The mechanism of action is to act on the 30S subunit of the bacterial ribosome and inhibit bacterial protein synthesis. Combination with semi-synthetic penicillins or cephalosporins often achieves a synergistic antibacterial effect.

This drug belongs to Class 2A, i.e., beta 1-receptor blockers without partial agonist activity (cardioselective beta 1-receptor blockers). It has a selective blocking effect on beta 1-receptors, no PAA (partial agonist activity), and no membrane stabilizing effect. Its effect on blocking beta 1-receptors is approximately equal to that of propranolol (PP), and its selectivity for beta 1-receptors is slightly inferior to that of atenolol. Metoprolol's effects on the heart, such as slowing heart rate, inhibiting cardiac contractility, reducing automaticity, and delaying atrioventricular conduction time, are similar to those of propranolol and atenolol (AT). Its effect on reducing elevated blood pressure and heart rate during exercise testing is also similar to that of PP and AT. Its contraction effect on vascular and bronchial smooth muscle is weaker than that of PP, so its effect on the respiratory tract is also smaller, but still stronger than that of AT. Metoprolol can also reduce plasma renin activity.

Used to adjust the solution to isotonic state, no direct pharmacological action is described.

It is a coenzyme necessary for many metabolic processes in the body and an important coenzyme for tissue respiration.

An important coenzyme component required for tissue respiration

It is a cofactor for many enzymes and is involved in the metabolism of amino acids and fats.

It is a component of coenzymes I and II and is necessary for lipid metabolism, oxidation of tissue respiration, and glycogenolysis.

It is a precursor of coenzyme A and is involved in the metabolism of carbohydrates, fats, and proteins.

It binds to the ribosome 50S subunit of sensitive microorganisms, inhibits RNA-dependent protein synthesis and exerts an antibacterial effect. It has a good antibacterial effect on Gram-positive cocci such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, and also has an inhibitory effect on Listeria, Moraxella catarrhalis, Neisseria gonorrhoeae and other pathogens.

It binds to the ribosome 50S subunit of sensitive microorganisms, inhibits RNA-dependent protein synthesis and exerts an antibacterial effect. It has a good antibacterial effect on Gram-positive cocci such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, and also has an inhibitory effect on Listeria, Moraxella catarrhalis, Neisseria gonorrhoeae and other pathogens.

It binds to the ribosome 50S subunit of sensitive microorganisms, inhibits RNA-dependent protein synthesis and exerts an antibacterial effect. It has a good antibacterial effect on Gram-positive cocci such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, and also has an inhibitory effect on Listeria, Moraxella catarrhalis, Neisseria gonorrhoeae and other pathogens.

It binds to the ribosome 50S subunit of sensitive microorganisms, inhibits RNA-dependent protein synthesis and exerts an antibacterial effect. It has a good antibacterial effect on Gram-positive cocci such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Enterococcus faecalis, and also has an inhibitory effect on Listeria, Moraxella catarrhalis, Neisseria gonorrhoeae and other pathogens.