This product is a third-generation cephalosporin antibiotic. It has high antibacterial activity against Escherichia coli, Klebsiella pneumoniae and other Enterobacteriaceae, Haemophilus influenzae, Pseudomonas aeruginosa, etc. It also has good antibacterial effects on nitrate-negative bacilli, Alcaligenes, etc. Most beta-lactamases produced by bacteria are highly stable, so it can still have antibacterial activity against multi-drug resistant strains of most of the above-mentioned Gram-negative bacilli. Gram-positive cocci such as pneumococci and hemolytic streptococci are highly sensitive to this product, but this product has only moderate activity against staphylococci, while enterococci and methicillin-resistant Staphylococci are often resistant to this product. This product has certain antibacterial activity against anaerobic bacteria such as Peptococcus and Peptostreptococci, but has poor antibacterial effect against Bacteroides fragilis. Its mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, acylate the transpeptidase, inhibit the synthesis of the bacterial septum and cell wall, affect the cross-linking of the cell wall mucopeptide components, inhibit cell division and growth, elongate the bacterial morphology, and finally dissolve and die.

Piperacillin is a semi-synthetic penicillin antibiotic with a broad-spectrum antibacterial effect. It has good antibacterial effects on Enterobacteriaceae such as Escherichia coli, Proteus, Serratia, Klebsiella, Enterobacter, Citrobacter, Salmonella and Shigella, as well as other Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, Haemophilus influenzae and Neisseria. It also has certain antibacterial activity against Enterococci, Group A and Group B hemolytic streptococci, Streptococcus pneumoniae and Staphylococci that do not produce penicillinase. Many anaerobic bacteria, including Bacteroides fragilis and Clostridium, are also sensitive to piperacillin. The mechanism of action of piperacillin is to exert a bactericidal effect by inhibiting bacterial cell wall synthesis.

Piperacillin is a semi-synthetic penicillin antibiotic with a broad-spectrum antibacterial effect. It has good antibacterial effects on Enterobacteriaceae such as Escherichia coli, Proteus, Serratia, Klebsiella, Enterobacter, Citrobacter, Salmonella and Shigella, as well as other Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, Haemophilus influenzae and Neisseria. It also has certain antibacterial activity against Enterococci, Group A and Group B hemolytic streptococci, Streptococcus pneumoniae and Staphylococci that do not produce penicillinase. Many anaerobic bacteria, including Bacteroides fragilis and Clostridium, are also sensitive to piperacillin. The mechanism of action of piperacillin is to exert a bactericidal effect by inhibiting bacterial cell wall synthesis.

Extract from the above information

Cefixime is a third-generation oral cephalosporin that kills bacteria by inhibiting bacterial cell wall synthesis. It is stable to most β-lactamases, and many strains producing penicillinase and cephalosporinase are still sensitive to this product. Cefixime has good antibacterial effects in vitro and in vivo against Gram-positive cocci such as pneumococci, Streptococcus pyogenes, and Gram-negative bacilli such as Haemophilus influenzae (including enzyme-producing strains), Moraxella catarrhalis (including enzyme-producing strains), Escherichia coli, Proteus mirabilis, and Neisseria gonorrhoeae (including enzyme-producing strains). Cefixime also has antibacterial activity against Streptococcus pneumoniae, Parainfluenzae, Proteus vulgaris, Klebsiella pneumoniae, Pasteurella multocida, Providencia, Salmonella, Shigella, Serratia marcescens, Citrobacter heteromorphis, and Citrobacter malonate, but its clinical effectiveness has not yet been established. This product has poor antibacterial effect on Staphylococcus, and has no antibacterial effect on Pseudomonas aeruginosa, Enterobacter, Bacteroides fragilis, Clostridium, etc.