This product is widely used to treat diabetic neuropathy. In vitro tests show that this product can reduce lipid oxidation in nerve tissues, and it may prevent the glycosylation of proteins; it can inhibit aldose reductase, thereby preventing glucose or galactose from being converted into sorbitol, so lipoic acid can prevent diabetes, control blood sugar, and prevent neuropathy caused by high blood sugar. Lipoic acid is a powerful antioxidant in both water-soluble and oil-soluble matrices. Both lipoic acid and its reduced form of dihydrolipoic acid can exert antioxidant effects. They can directly or indirectly promote the regeneration of vitamin C and vitamin E in the body. Studies have shown that lipoic acid can increase the levels of glutathione and coenzyme Q10 in cells. Lipoic acid can chelate certain metal ions.

This product can inhibit the synthesis of prostaglandins and has antipyretic and analgesic effects

Methylcobalamin is an endogenous coenzyme B12 that plays an important role as a coenzyme of methionine synthase in the transmethylation reaction of methionine synthesized from homocysteine. It is easily transferred to the organelles of nerve cells to promote the synthesis of nucleic acids and proteins. It participates in the synthesis of thymidine from deoxyuridine, promotes the utilization of folic acid and the metabolism of nucleic acids, and promotes intra-axonal transport and axonal regeneration.

Antipsychotic drugs block dopamine receptors (DA2) in the mesolimbic system and mesocortical pathways, and have blocking effects on dopamine (DA1) receptors, 5-hydroxytryptamine receptors, M-type acetylcholine receptors, and α-adrenaline receptors. At low doses, they can inhibit dopamine receptors in the medulla oblongata emetic chemoreceptor area, and at high doses, they can directly inhibit the vomiting center, producing a powerful antiemetic effect. They inhibit the body temperature regulation center, lower body temperature, block the action of peripheral α-adrenaline receptors, dilate blood vessels, cause a drop in blood pressure, and also have a certain effect on the endocrine system.

It competes with histamine released by tissues for H1 receptors, antagonizes the contraction or contracture of histamine on the gastrointestinal tract, trachea, bronchi or bronchiolar smooth muscle, and relieves the spasmodic and congestive effects of histamine on bronchial smooth muscle. The antiemetic effect may be related to the inhibition of the emetic chemoreceptor area of the medulla oblongata; the anti-dizziness effect may act on the vestibular and vomiting centers and midbrain medullary receptors through central anticholinergic properties, blocking the excitement of the labyrinthine impulses of the cholinergic synapses in the vestibular nucleus. It indirectly reduces the irritability of the ascending reticular activation system of the brainstem and plays a sedative and hypnotic role.