(1) Inhibit plasminogen activators, preventing plasminogen from activating into plasmin, thereby inhibiting the dissolution of fibrin and producing a hemostatic effect. (2) Promote the release of active substances from platelets, enhance platelet aggregation and adhesion, shorten coagulation time, and produce a hemostatic effect. (3) Enhance capillary resistance and reduce capillary permeability, thereby reducing bleeding.

By inhibiting the early synthesis of bacterial cell walls, bacterial cell wall synthesis is inhibited, leading to their death

Interfere with bacterial folic acid metabolism, selectively inhibit the activity of bacterial dihydrofolate reductase, prevent dihydrofolate from being reduced to tetrahydrofolate, and prevent the synthesis of bacterial nucleic acids and proteins

By inhibiting the early synthesis of bacterial cell walls, the bacterial cell wall synthesis is inhibited and leads to its death.

It interferes with bacterial folic acid metabolism and selectively inhibits the activity of bacterial dihydrofolate reductase, preventing dihydrofolate from being reduced to tetrahydrofolate, thereby preventing the synthesis of bacterial nucleic acids and proteins.

It has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has a bactericidal effect on Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis; it only has an antibacterial effect on anaerobic bacteria such as Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis, etc. Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus are usually resistant to chloramphenicol. Chloramphenicol is fat-soluble, enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of bacterial ribosomes, inhibiting the formation of peptide chains, thereby preventing protein synthesis.

This product belongs to the lincomycin antibiotics, which is a derivative of lincomycin. Its antibacterial spectrum is the same as that of lincomycin, and its antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus (including penicillin-resistant strains), Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against Gram-negative anaerobic bacteria. Most of the Bacteroides, including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, and Clostridium perfringens, are highly sensitive to this product. Gram-negative aerobic bacteria, including Haemophilus influenzae, Neisseria, and Mycoplasma, are resistant to this product. This product has no cross-resistance with penicillin, chloramphenicol, cephalosporins, and tetracyclines, has partial cross-resistance with macrolides, and has complete cross-resistance with lincomycin. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the elongation of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.