Effective for intestinal infections caused by Shigella dysenteriae and Escherichia coli

This product is an adrenal cortex hormone drug. External use can shrink dermal capillaries, inhibit the proliferation or regeneration of epidermal cells, inhibit the regeneration of fibroblasts in connective tissue, stabilize intracellular lysosomal membranes, and prevent tissue damage caused by the release of lysosomal enzymes. It has strong anti-inflammatory and anti-allergic effects.

As a histamine H1 receptor antagonist, this product can counteract capillary dilation caused by allergic reactions, reduce capillary permeability, and relieve wheezing caused by bronchial smooth muscle contraction; this product has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics; this product is mainly metabolized in the liver.

This product has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. It only has antibacterial effects on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are usually resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus. This product is an antibacterial agent. Chloramphenicol is fat-soluble and enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of the bacterial ribosome, which blocks the growth of the peptide chain (possibly due to the inhibition of the action of transpeptidase), thereby inhibiting the formation of the peptide chain and preventing protein synthesis.