Extracting pharmacological effects from the above information

Azithromycin is a 15-membered macrolide antibiotic. In vitro tests have shown that azithromycin has antibacterial effects on a variety of common pathogens in clinical practice, including Gram-positive aerobic bacteria (such as Staphylococcus aureus, Streptococcus pyogenes, etc.), Gram-negative aerobic bacteria (such as Haemophilus influenzae, Moraxella catarrhalis, etc.), anaerobic bacteria (such as Bacteroides fragilis), sexually transmitted disease microorganisms (such as Treponema pallidum, Neisseria gonorrhoeae, etc.) and other microorganisms (such as Borrelia tenuissima, Mycoplasma pneumoniae, etc.). The mechanism of action is the same as that of erythromycin, mainly binding to the 50S subunit of bacterial ribosomes and inhibiting RNA-dependent protein synthesis.

It can inhibit viral DNA and RNA polymerase, thereby inhibiting viral reproduction. On human embryonic kidney cells, 1% concentration has a significant inhibitory effect on DNA viruses (adenovirus, herpes virus) and RNA viruses (echovirus), and has an inhibitory effect on all stages of the viral proliferation cycle. It has no direct effect on free viral particles.