It inhibits bacterial protein synthesis by hindering the bacterial transpeptidation process. It has antibacterial effects on a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. The mechanism of action is the same as that of erythromycin, mainly binding to the 50S subunit of the bacterial ribosome to inhibit RNA-dependent protein synthesis.

This product forms nicotinamide adenine dinucleotide (coenzyme I) and nicotinamide adenine dinucleotide phosphate (coenzyme II) with ribose, phosphate and adenine in the body, which are necessary for lipid metabolism, oxidation of tissue respiration and glycogenolysis. Its deficiency can affect the normal respiration and metabolism of cells and cause pellagra.

The antibacterial spectrum is the same as that of lincomycin, and the antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against aerobic Gram-positive cocci, such as Staphylococcus (including penicillin-resistant and methicillin-sensitive strains), hemolytic streptococci, grass-green streptococci, and Streptococcus pneumoniae. It also has good antibacterial effects on anaerobic bacteria. Most of the genera, such as Bacteroides, Fusobacterium, Actinomyces, Peptococci, and Peptostreptococci are sensitive to this product. This product acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. It is generally an antibacterial agent, but at high concentrations, it also has a bactericidal effect on certain bacteria.

This product is a dihydropyridine calcium channel blocker that inhibits transmembrane calcium influx in vascular smooth muscle and myocardium, but mainly acts on blood vessels, so it has strong vascular selectivity. It causes dilation of systemic blood vessels such as coronary arteries and renal arterioles, producing a hypotensive effect.

The antibacterial spectrum is similar to that of rifampicin. It has good antibacterial activity against tuberculosis and leprosy. When the dosage is 1/3 of that of rifampicin, similar or higher efficacy can be achieved. It has a good effect on Staphylococcus aureus and has certain antibacterial activity against some Escherichia coli. In addition, it also has an inhibitory effect on Chlamydia trachomatis.