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Founded in:
2020-04-03 -
Country:
China -
Address:
The intersection of Guanggu Zong 1st Road and Heng 2nd Road, Chibi Avenue, Puqi, Chibi City, Xianning City, Hubei Province -
Tax NO.:
91421281MA49ETXF07 -
Registered Funds:
10 million yuan -
Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Nifedipine |
1. It is a dihydropyridine calcium antagonist that can selectively inhibit the transmembrane transport of calcium ions into myocardial cells and smooth muscle cells, and inhibit the release of calcium ions from intracellular pools without changing the plasma calcium ion concentration. 2. It can simultaneously dilate the coronary arteries in the normal blood supply area and the ischemic area, antagonize spontaneous or ergonovine-induced coronary artery spasm, increase the delivery of myocardial oxygen in patients with coronary artery spasm, relieve and prevent coronary artery spasm, and inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption. On the other hand, it can dilate peripheral resistance vessels, reduce peripheral resistance, reduce systolic and diastolic blood pressure, and reduce cardiac afterload. 3. It can delay the sinoatrial node function and atrioventricular conduction of isolated hearts, but electrophysiological studies of whole animals and humans have not found any effect of delaying atrioventricular conduction, prolonging the recovery time of the sinoatrial node, and slowing down the sinoatrial node rate.
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1. It is a dihydropyridine calcium antagonist that can selectively inhibit the transmembrane transport of calcium ions into myocardial cells and smooth muscle cells, and inhibit the release of calcium ions from intracellular pools without changing the plasma calcium ion concentration. 2. It can simultaneously dilate the coronary arteries in the normal blood supply area and the ischemic area, antagonize spontaneous or ergonovine-induced coronary artery spasm, increase the delivery of myocardial oxygen in patients with coronary artery spasm, relieve and prevent coronary artery spasm, and inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption. On the other hand, it can dilate peripheral resistance vessels, reduce peripheral resistance, reduce systolic and diastolic blood pressure, and reduce cardiac afterload. 3. It can delay the sinoatrial node function and atrioventricular conduction of isolated hearts, but electrophysiological studies of whole animals and humans have not found any effect of delaying atrioventricular conduction, prolonging the recovery time of the sinoatrial node, and slowing down the sinoatrial node rate. |
21829-25-4 | 74 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Gatifloxacin |
By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits bacterial DNA replication, transcription, and repair processes. It has antibacterial activity against the following microorganisms: 1. Gram-positive bacteria (such as Staphylococcus aureus, Streptococcus pneumoniae, etc.); 2. Gram-negative bacteria (such as Haemophilus, Moraxella catarrhalis, Neisseria, Acinetobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa, etc.); 3. Other microorganisms (such as Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae).
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By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits bacterial DNA replication, transcription, and repair processes. It has antibacterial activity against the following microorganisms: 1. Gram-positive bacteria (such as Staphylococcus aureus, Streptococcus pneumoniae, etc.); 2. Gram-negative bacteria (such as Haemophilus, Moraxella catarrhalis, Neisseria, Acinetobacter, Klebsiella pneumoniae, Pseudomonas aeruginosa, etc.); 3. Other microorganisms (such as Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae). |
112811-59-3 | 20 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Oridonin |
|
28957-04-2 | 0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Ribavirin |
A broad-spectrum antiviral drug that inhibits the growth of multiple viruses in vitro, including respiratory syncytial virus, influenza virus, hepatitis A virus, and adenovirus. After entering the virus-infected cells, the drug is rapidly phosphorylated, and its product acts as a competitive inhibitor of viral synthase, inhibiting inosine monophosphate dehydrogenase, influenza virus RNA polymerase, and mRNA guanosine transferase, thereby causing a reduction in intracellular guanosine triphosphate, impairing viral RNA and protein synthesis, and inhibiting viral replication and transmission. It may also have an immune effect and neutralizing antibody effect on respiratory syncytial virus.
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A broad-spectrum antiviral drug that inhibits the growth of multiple viruses in vitro, including respiratory syncytial virus, influenza virus, hepatitis A virus, and adenovirus. After entering the virus-infected cells, the drug is rapidly phosphorylated, and its product acts as a competitive inhibitor of viral synthase, inhibiting inosine monophosphate dehydrogenase, influenza virus RNA polymerase, and mRNA guanosine transferase, thereby causing a reduction in intracellular guanosine triphosphate, impairing viral RNA and protein synthesis, and inhibiting viral replication and transmission. It may also have an immune effect and neutralizing antibody effect on respiratory syncytial virus. |
36791-04-5 | 33 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Acyclovir |
Antiviral drug. It has an inhibitory effect on herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. in vitro. After entering the cells infected by herpes virus, this product competes with deoxynucleoside for viral thymidine kinase or cell kinase, and the drug is phosphorylated into activated acyclovir triphosphate, and then inhibits viral replication in two ways: ① Interfering with viral DNA polymerase and inhibiting viral replication; ② Under the action of DNA polymerase, it binds to the growing DNA chain, causing the extension of the DNA chain to be interrupted. This product has a special affinity for viruses, but has low toxicity to mammalian host cells.
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Antiviral drug. It has an inhibitory effect on herpes simplex virus, varicella zoster virus, cytomegalovirus, etc. in vitro. After entering the cells infected by herpes virus, this product competes with deoxynucleoside for viral thymidine kinase or cell kinase, and the drug is phosphorylated into activated acyclovir triphosphate, and then inhibits viral replication in two ways: ① Interfering with viral DNA polymerase and inhibiting viral replication; ② Under the action of DNA polymerase, it binds to the growing DNA chain, causing the extension of the DNA chain to be interrupted. This product has a special affinity for viruses, but has low toxicity to mammalian host cells. |
59277-89-3 | 50 |