Azithromycin is a 15-membered macrolide antibiotic that has antibacterial effects on a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. Its mechanism of action is the same as that of erythromycin, mainly binding to the 50S subunit of bacterial ribosomes and inhibiting RNA-dependent protein synthesis.

It has high antibacterial activity against most aerobic Gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae and Oxytobacter, Cloacae, Proteus, Serratia, Citrobacter, Shigella and other Enterobacteriaceae, as well as influenza bacilli, gonococci, meningococci, etc.; it also has good antibacterial effect on Pseudomonas aeruginosa; it inhibits the synthesis of bacterial cell wall by highly binding to penicillin-binding protein (PBP3) on the cell membrane of sensitive aerobic Gram-negative bacteria; it does not induce bacteria to produce b-lactamase, and is highly stable to most b-lactamases produced by bacteria.

It has high antibacterial activity against most aerobic Gram-negative bacteria, inhibiting the synthesis of bacterial cell walls by highly binding to penicillin-binding protein (PBP3) on the cell membrane of sensitive aerobic Gram-negative bacteria. It does not induce bacteria to produce b-lactamase, and is highly stable to most b-lactamases produced by bacteria.

Promotes the redox metabolism of brain cells, increases the utilization of carbohydrates, and has an excitatory effect on patients with central nervous system depression

It combines with pyrophosphate in the body to form a coenzyme, participates in the oxidative decarboxylation reaction of pyruvate and α-ketoglutarate in sugar metabolism, and is necessary for sugar metabolism. When it is deficient, oxidation is blocked to form pyruvate and lactic acid accumulation, which affects the body's energy supply and leads to symptoms of the nervous and cardiovascular systems, such as multiple peripheral neuritis (paresthesia, neuralgia, limb weakness, muscle aches and atrophy, etc.), cardiovascular dysfunction (palpitations, shortness of breath, chest tightness, cardiac hypertrophy, liver and lung congestion and peripheral edema, etc.), and digestive tract manifestations (loss of appetite, weakness, weight loss, etc.).