By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits bacterial DNA replication, transcription and repair processes. It has antibacterial activity against the following microorganisms: 1. Gram-positive bacteria: Staphylococcus aureus (limited to strains sensitive to methicillin), Streptococcus pneumoniae (strains sensitive to penicillin). 2. Gram-negative bacteria: Escherichia coli, Haemophilus influenzae and parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae, Proteus mirabilis. 3. Other microorganisms: Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae.

The results of the abnormal toxicity test on mice were qualified; it met the requirements for antihypertensive substances specified in the pharmacopoeia; it had no effect on guinea pigs, and the incidence rate of allergic reactions and the mortality rate were both 0; the maximum dosage for mice was greater than 100ml/kg, and no abnormal reactions were observed, and no animal deaths were caused.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation; protect brain tissue and have analgesic, sedative, anticonvulsant, anti-inflammatory, uterine excitation, and smooth muscle excitation effects

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation; protect brain tissue and have analgesic, sedative, anticonvulsant, anti-inflammatory, uterine excitation, and smooth muscle excitation effects

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation; protect brain tissue and have analgesic, sedative, anticonvulsant, anti-inflammatory, uterine excitation, and smooth muscle excitation effects

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation; protect brain tissue and have analgesic, sedative, anticonvulsant, anti-inflammatory, uterine excitation, and smooth muscle excitation effects

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, improve microcirculation, protect brain tissue, relieve pain, calm, resist convulsions, resist inflammation, excite the uterus, and excite smooth muscles

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, improve microcirculation, protect brain tissue, relieve pain, calm, resist convulsions, resist inflammation, excite the uterus, and excite smooth muscles

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, improve microcirculation, protect brain tissue, relieve pain, calm, resist convulsions, resist inflammation, excite the uterus, and excite smooth muscles

Increase coronary blood flow and myocardial nutritional blood flow, resist thrombosis and inhibit platelet aggregation, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, improve microcirculation, protect brain tissue, relieve pain, calm, resist convulsions, resist inflammation, excite the uterus, and excite smooth muscles

Increase coronary blood flow and myocardial nutritional blood flow, reduce total cholesterol, total esters, glyceryl trinitrate and esterified fatty acids in serum, anti-thrombosis, inhibit platelet aggregation, protect brain tissue, analgesic, sedative, anticonvulsant, anti-inflammatory, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation.

Increase coronary blood flow and myocardial nutritional blood flow, reduce total cholesterol, total esters, glyceryl trinitrate and esterified fatty acids in serum, anti-thrombosis, inhibit platelet aggregation, protect brain tissue, analgesic, sedative, anticonvulsant, anti-inflammatory, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation.

Increase coronary blood flow and myocardial nutritional blood flow, reduce total cholesterol, total esters, glyceryl trinitrate and esterified fatty acids in serum, anti-thrombosis, inhibit platelet aggregation, protect brain tissue, analgesic, sedative, anticonvulsant, anti-inflammatory, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation.

Increase coronary blood flow and myocardial nutritional blood flow, reduce total cholesterol, total esters, glyceryl trinitrate and esterified fatty acids in serum, anti-thrombosis, inhibit platelet aggregation, protect brain tissue, analgesic, sedative, anticonvulsant, anti-inflammatory, improve cellular hypoxia and the body's internal environment, increase blood flow to organs such as the heart, brain, and liver, and improve microcirculation.