It changes the cell membrane function by ① binding to the subunit of neutrophil microtubule protein, including inhibiting the chemotaxis, adhesion and phagocytosis of neutrophils; ② inhibiting phospholipase A2, reducing the release of prostaglandins and leukotrienes by monocytes and neutrophils; ③ inhibiting the production of interleukin-6 by local cells, thereby controlling the pain, swelling and inflammatory response of the joint. Colchicine does not affect the formation, dissolution and excretion of urate, and therefore has no effect on lowering blood uric acid.

This product is a blood lipid regulating drug of clofibric acid derivatives. Its mechanism of lowering blood lipids is not yet fully understood. It may reduce the cAMP content in liver microsomes, increase the activity of lipoprotein esterase, and decompose lipids in lipoproteins. Experimental and clinical studies have shown that this product reduces blood cholesterol and triglycerides and increases blood high-density lipoprotein. In addition, this product also has anti-platelet aggregation and anti-thrombotic effects and reduces blood uric acid.

Anti-amoebic effect; anti-trichomonal effect: Metronidazole has a direct killing effect on vaginal Trichomonas, and the cure rate of vaginal Trichomonas infection by local administration is 90%; anti-anaerobic effect; anti-Giardia effect; kills pathogens

This product is a glycine phosphoryl nitrogen mustard compound, which is a cyclophosphamide derivative, but does not require activation and can directly play an alkylating role. Its mechanism of action is mainly to inhibit DNA synthesis. Animal experiments show that the tumor inhibition rates for Yoshida sarcoma solid type and ascites type are 99.7% and 100% respectively, Wacker carcinosarcoma 256 is 91%, sarcoma S180 is 30%, reticular cell sarcoma L2 is 30%, and spindle cell sarcoma B22 is 45%. In tissue culture, it has a significant inhibitory effect on the proliferation and mitosis of Hela cells. In animal subacute toxicity experiments, dogs were given 20 mg/kg of glyphosate mustard daily for 10 consecutive days. There was no significant effect on red blood cells, hemoglobin, liver and kidney function, and no obvious gastrointestinal reaction. However, the inhibition of white blood cells and platelets has occurred, but it can return to normal after 2 days of drug withdrawal.

This product is a glycine phosphoryl nitrogen mustard compound, which is a cyclophosphamide derivative, but does not require activation and can directly play an alkylating role. Its mechanism of action is mainly to inhibit DNA synthesis. Animal experiments show that the tumor inhibition rates for Yoshida sarcoma solid type and ascites type are 99.7% and 100% respectively, Wacker carcinosarcoma 256 is 91%, sarcoma S180 is 30%, reticular cell sarcoma L2 is 30%, and spindle cell sarcoma B22 is 45%. In tissue culture, it has a significant inhibitory effect on the proliferation and mitosis of Hela cells. In animal subacute toxicity experiments, dogs were given 20 mg/kg of glyphosate mustard daily for 10 consecutive days. There was no significant effect on red blood cells, hemoglobin, liver and kidney function, and no obvious gastrointestinal reaction. However, the inhibition of white blood cells and platelets has occurred, but it can return to normal after 2 days of drug withdrawal.