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This product is a broad-spectrum antibacterial agent with bactericidal effect at high concentrations. In addition to common Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria, most Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria and spirochetes are also sensitive to this product. This product is better than Gram-positive bacteria for Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, etc. are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant gonococci are also resistant to tetracycline. This product has good antibacterial effect on Gram-negative bacteria such as Vibrio, Yersinia pestis, Brucella, Campylobacter, Yersinia, etc., has no antibacterial activity against Pseudomonas aeruginosa, and has certain antibacterial effect on some anaerobic bacteria.

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It belongs to the 14-membered macrolide antibiotics. The antibacterial spectrum is the same as that of erythromycin and roxithromycin, but it is slightly better against Gram-positive bacteria such as Streptococcus, Pneumococcus, and Staphylococcus, and it also has certain antibacterial activity against induced erythromycin-resistant strains. Clarithromycin and its metabolites in the body enhance the antibacterial effect on influenza bacilli. This product also has a certain effect on gonococci, Listeria, and Campylobacter jejuni, and has a stronger effect on Legionella pneumophila, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, etc. than erythromycin. It has a more prominent effect among the new varieties developed in recent years, with MIC90 of about 0.008-0.12 mg/L. In addition, it has a certain activity against Borrelia burgdorferi, Mycobacterium avium, Toxoplasma gondii, etc., and most of them are better than other varieties. In addition to having a strong antibacterial effect on anaerobic cocci, its effect on Bacteroides fragilis is better than erythromycin, etc. The post-antibiotic effect of this product on Staphylococcus aureus, Streptococcus pyogenes, Haemophilus influenzae, etc. is significantly stronger than erythromycin. This drug belongs to the macrolide antibiotics, and its mechanism is to inhibit the synthesis of proteins by hindering the association of the 50S subunit of the nucleoprotein. This drug has an inhibitory effect on Gram-positive bacteria such as Staphylococcus aureus, Streptococcus, and Pneumococcus, and also has an inhibitory effect on some Gram-negative bacteria such as Haemophilus influenzae, Bordetella pertussis, Gonorrhea, Legionella pneumophila, and some anaerobic bacteria such as Bacteroides fragilis, Streptococcus, and Propionibacterium acnes. In addition, it also has an inhibitory effect on mycoplasma. The characteristics of this drug are that its antibacterial activity in vitro is similar to that of erythromycin, but its antibacterial activity in vivo against some bacteria such as Staphylococcus aureus, Streptococcus, and Haemophilus influenzae is stronger than erythromycin. There is cross-resistance between it and erythromycin.