According to relevant standards and guidelines, tests were conducted on mice, guinea pigs and cats, and the results showed no abnormal toxic reactions, met the requirements of antihypertensive substances, had no allergic reactions and did not cause animal deaths.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

It is suitable for various types of shock, can excite the adrenal cortex system and increase the reticuloendothelial system's clearance of various pathological substances during shock, can improve the blood supply to important organs such as the heart, liver, and brain, improve microcirculation and anticoagulation effects; it is used for coronary heart disease, angina pectoris, myocardial infarction, viral myocarditis, cor pulmonale, heart failure, etc. It can strengthen the heart and increase blood pressure, improve coronary flow, increase the body's tolerance to hypoxia, reduce myocardial oxygen consumption, and protect and repair myocardial cells and have a certain anti-arrhythmic effect; for various cancer patients, it has obvious synergistic and toxic-reducing effects in combination with chemotherapy and radiotherapy, can improve the overall health of cancer patients, protect bone marrow hematopoietic function, improve the cellular immune function of tumor patients (increase NK, LAK activity and TH/TS value, etc.), and increase the rate of tumor disappearance and shrinkage.

It is suitable for various types of shock, can excite the adrenal cortex system and increase the reticuloendothelial system's clearance of various pathological substances during shock, can improve the blood supply to important organs such as the heart, liver, and brain, improve microcirculation and anticoagulation effects; it is used for coronary heart disease, angina pectoris, myocardial infarction, viral myocarditis, cor pulmonale, heart failure, etc. It can strengthen the heart and increase blood pressure, improve coronary flow, increase the body's tolerance to hypoxia, reduce myocardial oxygen consumption, and protect and repair myocardial cells and have a certain anti-arrhythmic effect; for various cancer patients, it has obvious synergistic and toxic-reducing effects in combination with chemotherapy and radiotherapy, can improve the overall health of cancer patients, protect bone marrow hematopoietic function, improve the cellular immune function of tumor patients (increase NK, LAK activity and TH/TS value, etc.), and increase the rate of tumor disappearance and shrinkage.

It is suitable for various types of shock, can excite the adrenal cortex system and increase the reticuloendothelial system's clearance of various pathological substances during shock, can improve the blood supply to important organs such as the heart, liver, and brain, improve microcirculation and anticoagulation effects; it is used for coronary heart disease, angina pectoris, myocardial infarction, viral myocarditis, cor pulmonale, heart failure, etc. It can strengthen the heart and increase blood pressure, improve coronary flow, increase the body's tolerance to hypoxia, reduce myocardial oxygen consumption, and protect and repair myocardial cells and have a certain anti-arrhythmic effect; for various cancer patients, it has obvious synergistic and toxic-reducing effects in combination with chemotherapy and radiotherapy, can improve the overall health of cancer patients, protect bone marrow hematopoietic function, improve the cellular immune function of tumor patients (increase NK, LAK activity and TH/TS value, etc.), and increase the rate of tumor disappearance and shrinkage.

It is suitable for various types of shock, can excite the adrenal cortex system and increase the reticuloendothelial system's clearance of various pathological substances during shock, can improve the blood supply to important organs such as the heart, liver, and brain, improve microcirculation and anticoagulation effects; it is used for coronary heart disease, angina pectoris, myocardial infarction, viral myocarditis, cor pulmonale, heart failure, etc. It can strengthen the heart and increase blood pressure, improve coronary flow, increase the body's tolerance to hypoxia, reduce myocardial oxygen consumption, and protect and repair myocardial cells and have a certain anti-arrhythmic effect; for various cancer patients, it has obvious synergistic and toxic-reducing effects in combination with chemotherapy and radiotherapy, can improve the overall health of cancer patients, protect bone marrow hematopoietic function, improve the cellular immune function of tumor patients (increase NK, LAK activity and TH/TS value, etc.), and increase the rate of tumor disappearance and shrinkage.