Mirtazapine is a presynaptic alpha 2 receptor antagonist that acts on the central nervous system and can enhance adrenergic neurotransmission. It regulates the function of 5-hydroxytryptamine by interacting with the central 5-hydroxytryptamine receptors (5-HT2, 5-HT3). Both optical enantiomers of mirtazapine have antidepressant activity, the left-handed form blocks alpha 2 and 5-HT2 receptors, and the right-handed form blocks 5-HT3 receptors. The antihistamine receptor (H1) property of mirtazapine plays a sedative role. The drug has good tolerance and almost no anticholinergic effect. Its therapeutic dose has no effect on the cardiovascular system. It is suitable for depression and is effective for symptoms such as lack of pleasure, psychomotor inhibition, poor sleep (early awakening) and weight loss. It can also be used for other symptoms such as loss of interest in things, suicidal tendencies and mood swings (good at night, bad in the morning). Remeron takes effect one to two weeks after taking the drug.

Urapidil is a highly selective α1 receptor blocker with both peripheral and central effects. The peripheral vasodilator effect is mainly to block postsynaptic α1 receptors, which significantly reduces peripheral resistance. At the same time, it also has a moderate vasoconstrictor effect of blocking catecholamines. The central effect is to reduce blood pressure by stimulating serotonin-1A receptors and reducing the sympathetic feedback regulation of the medullary cardiovascular center. At the same time, it can also improve various hemodynamic indicators by reducing the side effect of reflex heart rate acceleration.

Nimodipine is a Ca2 channel blocker that inhibits smooth muscle contraction by preventing Ca2 from entering cells, thereby relieving vasospasm. It has a strong effect on cerebral arteries and easily penetrates the blood-brain barrier. It can be used to prevent vasospasm after subarachnoid hemorrhage. It also has the effect of protecting and promoting memory.

1. This product is a second-generation sulfonylurea antidiabetic drug, which is effective for most patients with type 2 diabetes. It can reduce fasting and postprandial blood sugar and reduce glycosylated hemoglobin (HbAlc) by 1% to 2%. 2. The main function of this type of drug is to stimulate the pancreatic b cells to secrete insulin, but the prerequisite is that the pancreatic b cells still have a certain function of synthesizing and secreting insulin. 3. Its mechanism is to specifically bind to the sulfonylurea receptor on the b cell membrane, thereby closing the K channel, causing changes in membrane potential, opening the Ca2 channel, and increasing intracellular Ca2, forcing insulin secretion. 4. In addition, there are extrapancreatic effects, including improving the insulin resistance of peripheral tissues (such as liver, muscle, and fat).

Supplement calories, treat hypoglycemia, treat hyperkalemia when used in combination with insulin, rapid intravenous injection of hypertonic glucose injection has the effect of tissue dehydration, maintain and regulate the osmotic pressure of peritoneal dialysis fluid