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Potassium chloride tablets

Function and Efficacy

Potassium is the main cation in cells, with a concentration of 150-160mmol/L, while the main cation outside cells is sodium ion, and the serum potassium concentration is only 3.5-5.0mmol/L. The body mainly relies on Na-K-ATPase on the cell membrane to maintain the difference in K and Na concentrations in cells. The acid-base balance in the body has an impact on potassium metabolism. For example, when acidosis occurs, H enters the cell. In order to maintain the potential difference inside and outside the cell, K is released outside the cell, causing or aggravating hyperkalemia. Metabolic disorders can also affect acid-base balance. The normal intracellular and extracellular potassium ion concentration and concentration difference are closely related to certain important functions of cells, including maintaining carbohydrate metabolism, glycogen storage, protein metabolism, intracellular osmotic pressure and acid-base balance, and myocardial excitability.

Ingredients

The main ingredients of this product and its chemical name: Potassium chloride

Name Description Content CAS NO. Manufacturer
Potassium chlorideIngredients

Potassium is the main cation in cells, with a concentration of 150-160mmol/L, while the main cation outside cells is sodium ions, and the serum potassium concentration is only 3.5-5.0mmol/L. The body mainly relies on the Na-K-ATPase on the cell membrane to maintain the concentration difference between K and Na in cells. The acid-base balance in the body has an impact on potassium metabolism. For example, when acidosis occurs, H enters the cell. In order to maintain the potential difference between the inside and outside of the cell, K is released outside the cell, causing or aggravating hyperkalemia. Metabolic disorders can also affect acid-base balance. The normal potassium ion concentration and concentration difference inside and outside the cell are closely related to some important functions of the cell, including maintaining carbohydrate metabolism, glycogen storage, protein metabolism, intracellular osmotic pressure and acid-base balance, and myocardial excitability.

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7447-40-7 39

Appearance

This product is white or slightly yellow granules.

Indication

1 Treatment of hypokalemia Hypokalemia caused by various reasons, such as insufficient food intake, vomiting, severe diarrhea, and the use of potassium-excreting diuretics. Hypokalemic familial periodic paralysis, long-term use of glucocorticoids, and supplementation of hypertonic glucose, etc. 2 Prevention of hypokalemia When the patient has potassium loss, especially if hypokalemia is harmful to the patient (such as patients using digitalization), preventive potassium salt supplementation is required, such as eating very little, severe or chronic diarrhea, long-term use of adrenocortical hormones, potassium-losing nephropathy, and Bartter syndrome, etc. 3 Digitalis poisoning causes frequent, multi-source premature beats or rapid arrhythmias.

Usage and Dosage

Oral potassium salts are used to treat mild hypokalemia or as preventive medication. The usual dose for adults is 0.5-1g (6.7-13.4mmol) each time, dissolved in warm water and taken 1-3 times a day, after meals, and the dose is adjusted according to the condition. The maximum daily dose for adults is 6g (80mmol).

Adverse Reactions

1 Oral administration may cause gastrointestinal irritation symptoms, such as nausea, vomiting, throat discomfort, chest pain (esophageal irritation), abdominal pain, diarrhea, and even peptic ulcer and bleeding. It is more likely to occur on an empty stomach, in large doses, or in patients with existing gastrointestinal diseases. 2 Hyperkalemia should be noted in patients with existing renal impairment.

Precautions

Contraindicated in patients with hyperkalemia.

Drug Interactions

1. Adrenal glucocorticoids, especially those with more obvious mineralocorticoid effects, adrenal mineralocorticoids and adrenocorticotropic hormone (ACTH), can promote urinary potassium excretion, and when used in combination with this product, the efficacy of potassium salts will be reduced. 2. Anticholinergic drugs can aggravate the gastrointestinal irritation of oral potassium salts, especially potassium chloride. 3. Non-steroidal anti-inflammatory analgesics aggravate the gastrointestinal reactions of oral potassium salts. 4. When used in combination with stored blood (containing 30mmol/L potassium for less than 10 days of storage, 65mmol/L potassium for more than 10 days of storage), potassium-containing drugs and potassium-sparing diuretics, the chance of hyperkalemia increases, especially in patients with renal damage. 5. Blood

Storage

Keep tightly closed.

Packaging Specification

0.25g

Manufacturer

Taishan City Xinning Pharmaceutical Co., Ltd.

  • Founded in:

    2005-06-24
  • Address:

    No. 223, Renxiao Road, Taicheng Town, Taishan City
  • Tax NO.:

    91440781776913130X
  • Registered Funds:

    100 million yuan
  • Email:

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