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Menadione Acetate Tablets

Function and Efficacy

Vitamin K is a necessary substance for the liver to synthesize coagulation factors II, VII, IX and X. Vitamin K deficiency can cause synthesis disorders of these coagulation factors, and clinically bleeding tendency and prolonged prothrombin time can be seen. These factors are usually called vitamin K-dependent coagulation factors. The exact mechanism by which vitamin K promotes the synthesis of factors II, VII, IX and X has not yet been elucidated. Natural vitamin K includes K1 and K2, which are fat-soluble and their absorption depends on the normal secretion of bile. Artificially synthesized vitamin K includes K3 and K4. The former is sodium bisulfite menadione and the latter is acetyl menadione, which are water-soluble and do not require the presence of bile for absorption.

Ingredients

The main ingredients of this product are: Menadione Acetate

Name Description Content CAS NO. Manufacturer
Menadiol diacetateIngredients

Vitamin K is a substance necessary for the liver to synthesize coagulation factors II, VII, IX and X. Vitamin K deficiency can cause synthesis disorders of these coagulation factors, and clinically, bleeding tendency and prolonged prothrombin time can be seen. Natural vitamin K includes K1 and K2, which are fat-soluble and their absorption depends on the normal secretion of bile. Artificially synthesized vitamin K includes K3 and K4, the former is sodium bisulfite menadione, and the latter is acetyl menadione, which are water-soluble and do not require the presence of bile for their absorption.

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Appearance

This product is a sugar-coated tablet, which appears white or slightly yellow after removing the sugar coating.

Indication

Vitamin K is a necessary substance for the liver to synthesize coagulation factors II, VII, IX and X. Vitamin K deficiency can cause synthesis disorders of these coagulation factors, and clinically bleeding tendency and prolonged prothrombin time can be seen. These factors are usually called vitamin K-dependent coagulation factors. The exact mechanism by which vitamin K promotes the synthesis of factors II, VII, IX and X has not yet been elucidated. Natural vitamin K includes K1 and K2, which are fat-soluble and their absorption depends on the normal secretion of bile. Artificially synthesized vitamin K includes K3 and K4. The former is sodium bisulfite menadione and the latter is acetyl menadione, which are water-soluble and do not require the presence of bile for absorption.

Usage and Dosage

Oral administration, 2-4 mg (0.5-1 tablet) at a time, 3 times a day.

Adverse Reactions

Oral administration may cause gastrointestinal reactions such as nausea and vomiting. Use with caution in patients with severe liver disease.

Precautions

Not yet clear

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: This product can pass through the placenta, so pregnant women in labor should try to avoid using this product. Precautions for the elderly: Not yet clear.

Drug Interactions

Oral anticoagulants such as dicoumarol can interfere with the metabolism of vitamin K. When the two drugs are used together, their effects cancel each other out. Salicylates, sulfonamides, quinidine, etc. can also affect the effects of vitamin K.

Storage

Keep away from light and store in sealed container.

Packaging Specification

5mg

Validity Period

24 months

Manufacturer

China Resources Zizhu Pharmaceutical Co., Ltd.

  • Founded in:

    1980-11-26
  • Address:

    Building 18, No. 27 Chaoyang North Road, Chaoyang District, Beijing
  • Tax NO.:

    91110000101939631P
  • Registered Funds:

    660.6396 million yuan
  • Website:

  • Email:

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