Lovastatin Tablets

This product competitively inhibits the rate-limiting enzyme hydroxymethylglutaryl coenzyme A reductase in the cholesterol synthesis process in the body, reducing the synthesis of cholesterol and increasing the synthesis of low-density lipoprotein receptors. The main site of action is in the liver, resulting in lower blood cholesterol and low-density lipoprotein cholesterol levels, thereby playing a role in the prevention and treatment of atherosclerosis and coronary heart disease. This product also reduces serum triglyceride levels and increases blood high-density lipoprotein levels.

The main ingredient of this product is: Lovastatin.

This product is white or off-white tablets.

Used to treat hypercholesterolemia and combined hyperlipidemia.

The usual oral dose for adults is 10-20 mg (0.5-1 tablet), once a day, taken at dinner. The dose can be adjusted as needed, but the maximum dose should not exceed 80 mg (4 tablets) per day.

1. The most common adverse reactions of this product are gastrointestinal discomfort, diarrhea, flatulence, and others include headache, rash, dizziness, blurred vision, and taste disturbance. 2. It may occasionally cause a reversible increase in blood aminotransferase. Therefore, liver function needs to be monitored. 3. Rare adverse reactions include impotence and insomnia. 4. Rare adverse reactions include myositis, myalgia, and rhabdomyolysis, which manifest as muscle pain, fatigue, fever, and are accompanied by increased blood creatine phosphokinase and myoglobinuria. Rhabdomyolysis can lead to renal failure, but it is rare. The combination of this product with immunosuppressants, folic acid derivatives, niacin, gemfibrozil, erythromycin, etc. may increase the risk of myopathy. 5. Hepatitis, pancreatitis, and allergic reactions such as angioedema have been reported.

1. Patients who are allergic to lovastatin are contraindicated. Patients who are allergic to other HMG-CoA reductase inhibitors should use with caution. 2. Patients with active liver disease or unexplained persistent elevation of blood aminotransferase are contraindicated.

1. The combination of this product with oral anticoagulants can prolong the prothrombin time and increase the risk of bleeding. 2. The combination of this product with immunosuppressants such as cyclosporine, azithromycin, clarithromycin, erythromycin, danazol, itraconazole, gemfibrozil, niacin, etc. can increase the risk of myolysis and acute renal failure. 3. Colestipol and cholestyramine can reduce the bioavailability of this product, so this product should be taken 4 hours after taking the former.

Keep in a dark place, sealed and stored at room temperature (10~30℃).

20mg

Livzon (GROUP) Pharmaceutical FACTORY

• Founded in:

  1989-11-26

• Address:

  No. 38 Chuangye North Road, Jinwan District, Zhuhai City

• Tax NO.:

  91440400617489061P

• Registered Funds:

  450 million yuan

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