Cephalexin and Trimethoprim Capsules

This product inhibits bacterial transpeptidase, prevents the synthesis of bacterial cell walls, and inhibits or kills bacteria. The combination of cephalexin and trimethoprim improves the antibacterial ability, delays the development of drug resistance, and reduces the oral dose.

Each tablet contains 125mg of cephalexin and 25mg of trimethoprim

This product is a capsule, and the contents are white or off-white crystalline powder.

Used for infections caused by penicillin-resistant Staphylococci, Streptococci, Pneumococci, Escherichia coli, etc.

It is recommended to be taken orally on an empty stomach. Adults take 1-2 tablets at a time, 4 times a day. Children should take a reduced dosage or follow the doctor's advice.

1. Nausea, vomiting, diarrhea and abdominal discomfort are more common. 2. Allergic reactions such as rash and drug fever are rare, and anaphylactic shock may occur occasionally. 3. Neurological reactions such as dizziness, diplopia, tinnitus, and convulsions. 4. Renal damage may occur occasionally during the use of this product. 5. Occasionally, patients have elevated serum aminotransferases and positive Coombs tests. Hemolytic anemia is rare. Neutropenia and pseudomembranous colitis have also been reported. 6. Trimethoprim's interference with folic acid metabolism can produce adverse reactions in the blood system, such as leukopenia, thrombocytopenia or methemoglobin anemia. Generally, leukopenia and thrombocytopenia are mild, and can be recovered by stopping the drug in time. Folic acid preparations can also be added.

1. It is contraindicated for those who are allergic to cephalosporins or penicillin. 2. It is contraindicated for those who are allergic to trimethoprim. 3. It is contraindicated for newborns and premature infants. 4. It is contraindicated for patients with severe liver and kidney diseases. 5. It is contraindicated for patients with blood diseases. 6. This product can pass through the placenta and is also excreted through breast milk, so pregnant and lactating women should use it with caution.

Precautions for children: It is forbidden to use in newborns and premature infants. Precautions for pregnancy and lactation: This product can pass through the placenta and be excreted through breast milk, so pregnant and lactating women should use it with caution. Precautions for the elderly: It is not clear yet.

1. When used in combination with cholestyramine (cholestyramine), the average blood concentration of cephalexin can be reduced. 2. Probenecid can delay the renal excretion of this product, and there are also reports that probenecid can increase the excretion of this product in bile. 3. When bone marrow suppressants are used in combination with this product, the chance of leukopenia and thrombocytopenia increases. 4. This product should not be used simultaneously with anti-tumor drugs 2,4-diaminopyrimidine drugs, nor should it be used between courses of treatment with other folic acid antagonists, because it may cause bone marrow aplasia or megaloblastic anemia. 5. Co-use of cyclosporine can increase renal toxicity.

Keep in a dark, sealed and cool place

0.15g (C16H17N3O4S 0.125g and C14H18N4O3 0.025g)

24 months

Shandong Zibo Xinda Pharmaceutical Co., Ltd.

• Founded in:

  1993-03-11

• Address:

  No. 1, Lutai Avenue, Zibo High-tech Zone

• Tax NO.:

  9137030361328152XT

• Registered Funds:

  84.93 million yuan

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