Fosfomycin calcium tablets

This product is a broad-spectrum antibiotic. It inhibits the early synthesis of bacterial cell walls, which leads to the death of bacteria. This product has a wide antibacterial spectrum and has a certain antibacterial effect on most Gram-positive and Gram-negative bacteria. The antibacterial spectrum of this product includes Staphylococcus aureus, Escherichia coli, Shigella, Serratia, Shigella, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterobacter aerogenes.

The main ingredient is fosfomycin, and its chemical name is: L-cis-1,2-epoxypropyl calcium phosphate. Its structural formula is: Molecular formula: C3H5CaO4P·H2O Molecular weight: 194.14

This product is white or off-white tablets

Oral administration is suitable for the following infections caused by pathogens sensitive to fosfomycin: 1. Intestinal infections: bacterial enteritis, bacillary dysentery. 2. Urinary tract infections: cystitis, pyelonephritis, urethritis. 3. Dermatological and soft tissue infections: furunculosis, anthrax, sweat gland inflammation, lymphadenitis, folliculitis. 4. Respiratory tract infections: nasopharyngitis, tonsillitis, tracheitis, early chronic bronchitis. 5. Ophthalmology: sty, dacryocystitis. 6. Gynecology: vaginitis, cervicitis.

For oral administration, adults take 2-4 g of fosfomycin acid per day; children take 50-100 mg/kg per day based on body weight, divided into 3-4 doses.

Mainly mild gastrointestinal reactions, such as nausea, decreased appetite, upper abdominal discomfort, loose stools or mild diarrhea, etc. Generally, it does not affect the continued use of the drug. Occasionally, skin rash, eosinophilia, and elevated alanine aminotransferase may occur. No toxic reactions to the kidneys or blood system were observed.

Not yet clear.

Precautions for children: This experiment has not been conducted, and there is no reliable reference. Precautions for pregnancy and lactation: Use with caution in pregnant women. Uncertain for lactating women. Precautions for the elderly: This experiment has not been conducted, and there is no reliable reference.

1. It has a synergistic effect when used in combination with beta-lactams against Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus) and Pseudomonas aeruginosa. 2. It has a synergistic effect when used in combination with aminoglycosides. 3. There is no cross-resistance with other antibiotics.

Sealed and stored in a dry place. Valid for two years

0.14g (calculated as C3H7O4P)

Tentative 24 months