Alendronate Sodium Tablets
Function and Efficacy
This product is a bone metabolism regulator, an aminobisphosphonate, which has a strong affinity with hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition.
Ingredients
The main ingredient of this product is alendronate sodium
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Alendronate sodiumIngredients |
Bone metabolism regulator, an aminobisphosphonate, has a strong affinity with hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition. More |
121268-17-5 | 38 |
Appearance
This product is white tablets.
Indication
1. For the treatment of osteoporosis in postmenopausal women. 2. For the prevention of hip and spinal fractures (vertebral compression fractures).
Usage and Dosage
Take orally with 200 ml of warm water on an empty stomach at least 30 minutes before breakfast, 10 mg at a time, once a day.
Adverse Reactions
Abdominal pain, diarrhea, nausea, constipation, indigestion. If the prescribed dosage is not followed, esophageal ulcer may occur. Occasionally, blood calcium may be reduced, white blood cell count may increase temporarily, and red blood cells and white blood cells in urine may increase.
Precautions
It is contraindicated for patients with esophageal motility disorders, such as esophageal atony and esophageal stenosis, severe renal damage, and osteomalacia.
Special Population Medication
Precautions for children: Long-term use may affect bone metabolism and should be used with caution. Precautions for pregnancy and lactation: Safety is unclear and should not be used. Precautions for the elderly: Not yet clear.
Drug Interactions
1. Antacids and cathartics often contain calcium or other metal ions such as magnesium and iron, which may affect the absorption of this drug. 2. Combination with aminoglycosides may induce hypocalcemia.
Storage
Protect from light, seal tightly and store in a cool place.
Packaging Specification
10 mg (as alendronic acid)
Validity Period
42 months
Manufacturer
Hainan Quanxing Pharmaceutical Co., Ltd.
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Founded in:
2001-10-29 -
Address:
A06-2, Bonded Area, Haikou City, Hainan Province -
Tax NO.:
91460000730066028H -
Registered Funds:
54.29 million yuan -
Website:
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Email: