Chlorpromazine Hydrochloride Tablets

This product is a phenothiazine antipsychotic, and its mechanism of action is mainly related to its blocking of dopamine receptors (DA2) in the mesolimbic system and mesocortical pathways. It has a blocking effect on dopamine (DA1) receptors, 5-hydroxytryptamine receptors, M-type acetylcholine receptors, and α-adrenaline receptors, and has a wide range of effects. In addition, this product can inhibit the dopamine receptors in the medulla oblongata emetic chemoreceptor area at low doses, and directly inhibit the vomiting center at high doses, producing a strong antiemetic effect. It inhibits the body temperature regulation center and lowers the body temperature. The body temperature can change with changes in the external environment. It blocks the action of peripheral α-adrenaline receptors, dilates blood vessels, causes a drop in blood pressure, and also has a certain effect on the endocrine system.

The main ingredient of this product is chlorpromazine hydrochloride, and its chemical name is: N,N-dimethyl-2-chloro-10H-phenothiazine-10-propylamine hydrochloride.

This product is a sugar-coated tablet, which appears white after removing the sugar coating.

1. It has a good effect on positive symptoms such as excitement, agitation, hallucination, delusion, thinking disorder and behavioral disorder. It is used for schizophrenia, mania or other psychotic disorders. 2. It can stop vomiting, vomiting or intractable hiccups caused by various reasons.

Oral use for schizophrenia or mania, starting with a low dose, 25-50 mg once, 2-3 times a day, slowly increasing every 2-3 days to 25-50 mg once, the therapeutic dose is 400-600 mg a day. For other mental illnesses, the dose should be smaller. The dose for the weak should be smaller and should be increased slowly. For vomiting, 12.5-25 mg once, 2-3 times a day.

1 Common symptoms include dry mouth, upper abdominal discomfort, loss of appetite, fatigue and drowsiness. 2 May cause postural hypotension, palpitations or electrocardiographic changes. 3 Extrapyramidal reactions may occur, such as tremor, rigidity, drooling, bradykinesia, akathisia, and acute dystonia. 4 Long-term and large-scale medication may cause tardive dyskinesia. 5 May cause increased plasma prolactin concentrations, and possible related symptoms include galactorrhea, gynecomastia, menstrual disorders, and amenorrhea. 6 May cause toxic liver damage or obstructive jaundice. 7 Rare bone marrow suppression. 8 Occasionally may cause epilepsy

Patients with basal ganglia lesions, Parkinson's disease, Parkinson's syndrome, bone marrow suppression, glaucoma, coma and allergy to phenothiazines.

1. When this product is used in combination with ethanol or other central nervous system depressants, the central depressant effect is enhanced. 2. When this product is used in combination with antihypertensive drugs, it is easy to cause postural hypotension. 3. When this product is used in combination with sultopride, there is a risk of ventricular arrhythmia, and in severe cases, it can cause torsade de pointes arrhythmia. 4. When this product is used in combination with atropine drugs, the adverse reactions are enhanced. 5. When this product is used in combination with lithium carbonate, it can cause an increase in blood lithium concentration. 6. Antacids can reduce the absorption of this product, and phenobarbital can accelerate its excretion, thereby weakening its antipsychotic effect. 7. This product is combined with monoamine oxidase inhibitors and tricyclic antipsychotics.

Keep away from light and store in sealed container.

25mg

Guangdong Heping Pharmaceutical Co., Ltd.

• Founded in:

  2002-09-10

• Address:

  No. 21 Shanhu Road, Heping County, Guangdong

• Tax NO.:

  91441624742971842K

• Registered Funds:

  17.5 million yuan

• Email:

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