Fleroxacin Injection

This product is a fluoroquinolone antibacterial drug. It has strong antibacterial effects on Gram-negative bacteria, including Escherichia coli, Klebsiella pneumoniae, Proteus, Salmonella typhi, Salmonella paratyphi, Shigella, Enterobacter cloacae, Enterobacter aerogenes, Citrobacter, Serratia marcescens, Pseudomonas aeruginosa, Neisseria meningitidis, Haemophilus influenzae, Moracata, Legionella pneumophila, Neisseria gonorrhoeae, etc. It also has moderate antibacterial effects on Gram-positive cocci such as Staphylococcus and hemolytic Streptococcus. In recent years, bacterial resistance to fluoroquinolones has increased significantly, especially in Escherichia coli, with a resistance rate of more than 50%. The mechanism of action of this product is to inhibit the bacterial DNA gyrase and thus kill bacteria.

The main ingredient of this product is fleroxacin [molecular formula] C17H18F3N3O3 [molecular weight] 369.34

This product is a yellow-green clear liquid

It can be used for respiratory system infections such as acute bronchitis, acute exacerbation of chronic bronchitis and pneumonia caused by bacteria sensitive to this product; urogenital system infections such as cystitis, pyelonephritis, prostatitis, epididymitis, gonorrhea Neisseria urethritis; digestive system infections such as typhoid Salmonella infection and bacterial dysentery; skin and soft tissue infections, bone infections, abdominal infections and pelvic infections, etc.

Inject slowly by intravenous drip in a dark place, 0.2-0.4 g at a time, once a day, diluted in 250-500 ml 5% glucose injection.

1. Gastrointestinal reactions are relatively common and may manifest as abdominal discomfort or pain, diarrhea, nausea and vomiting, and loss of appetite. 2. Central nervous system reactions may include dizziness, headache, excitement, drowsiness or insomnia. 3. Allergic reactions include rash and skin itching, and occasionally exudative erythema multiforme and angioneurotic edema. A small number of patients have photosensitivity reactions. 4. A small number of patients may experience increased blood aminotransferase and blood urea nitrogen and decreased peripheral blood white blood cells, which are mostly mild and transient. 5. Occasionally, the following may occur: (1) Epileptic seizures, mental abnormalities, irritability, confusion, hallucinations, and tremors. (2) Interstitial nephritis manifestations such as hematuria, fever, and rash. (3) Crystalluria, which is more common when high doses are used. (4) Joint pain. (5) Phlebitis.

1. Those who are allergic to this product or quinolones are contraindicated. 2. Pregnant women, lactating women and patients under 18 years old are contraindicated. [Use in pregnant and lactating women] Fluoroquinolones can pass through the blood-placental barrier and can be secreted into breast milk. Their concentration is close to the blood drug concentration, so pregnant and lactating women are contraindicated. [Use in children] Fluoroquinolones can cause permanent damage to the weight-bearing joint cartilage of dogs and cause lameness. They can also cause arthritis in several other minor animals, so they are contraindicated for patients under 18 years old. In infections caused by multidrug-resistant bacteria, when the bacteria are only sensitive to fluoroquinolones, this product can only be used in children after weighing the pros and cons. [Use in the elderly] Elderly patients have reduced renal function, and the dosage should be reduced as appropriate.

1. The aluminum and magnesium contained in didanosine preparations can chelate with fluoroquinolones and should not be used together. 2. Urine alkalinizers can reduce the solubility of this product in urine, leading to crystalluria and nephrotoxicity. 3. Probenecid can delay the excretion of this product, increase the blood concentration of this product and produce toxicity.

Keep in dark, airtight and cool place

2ml:0.2g

Dalian Wanda Commercial Management Group Co.,Ltd

• Founded in:

  1997-08-28

• Address:

  No. 8 Yaogu 2nd Road, Xiuying District, Haikou City

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  914601002939678125

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