Metronidazole and glucose injection
Function and Efficacy
This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1-2 mg/L, the histolytica can undergo morphological changes in 6-20 hours and all are killed within 24 hours. When the concentration is 0.2 mg/L, the histolytica can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on anaerobic microorganisms, and the metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. Metronidazole is carcinogenic to some animals.
Ingredients
This product is a compound preparation, its components are: metronidazole 0.2%, glucose 5%.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| MetronidazoleIngredients |
This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1-2 mg/L, the histolytica amoeba can undergo morphological changes in 6-20 hours and all are killed within 24 hours. When the concentration is 0.2 mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on anaerobic microorganisms, and the metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. Metronidazole is carcinogenic to some animals. More |
443-48-1 | 39 | |
| GLUCOSEExcipients |
This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1-2 mg/L, the histolytica can undergo morphological changes in 6-20 hours and all are killed within 24 hours. When the concentration is 0.2 mg/L, the histolytica can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on anaerobic microorganisms, and the metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death. Metronidazole is carcinogenic to some animals. More |
58367-01-4 | 15 |
Indication
Mainly used to treat anaerobic infections
Usage and Dosage
Intravenous drip. 1 Common dosage for adults: For anaerobic infection, the first dose is 15 mg/kg (1 g for a 70 kg adult) by intravenous drip, and the maintenance dose is 7.5 mg/kg by intravenous drip every 6 to 8 hours. 2 Common dosage for children: The injection dose for anaerobic infection is the same as that for adults.
Adverse Reactions
Adverse reactions occur in 15% to 30% of cases, with gastrointestinal reactions being the most common, including nausea, vomiting, loss of appetite, and abdominal cramps, which generally do not affect treatment; neurological symptoms include headache, dizziness, occasional paresthesia, limb numbness, ataxia, multiple neuritis, etc., and large doses can cause convulsions. A small number of cases develop urticaria, hot flashes, itching, cystitis, dysuria, metallic taste in the mouth, and leukopenia, all of which are reversible and recover on their own after stopping the drug.
Precautions
It is contraindicated for patients with active central nervous system diseases and blood diseases.
Drug Interactions
This product can enhance the effect of anticoagulant drugs such as warfarin.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
250ml: Metronidazole 0.5g and glucose 12.5g