Amantadine Hydrochloride Tablets

This product was originally an antiviral drug. Its anti-Parkinson's disease mechanism is mainly to promote the synthesis and release of striatal dopamine, reduce the reuptake of dopamine by nerve cells, and have an anti-acetylcholine effect, thereby improving the symptoms of Parkinson's patients.

The main ingredient of this product is adamantane hydrochloride, and its chemical name is: tricyclo[3,3,1,13,7]decane-1-amine hydrochloride. Its structural formula is: C10H17NHCl187.71

This product is white tablets.

It is used for Parkinson's disease, Parkinson's syndrome, drug-induced extrapyramidal disorders, Parkinson's syndrome after carbon monoxide poisoning, and Parkinson's syndrome in the elderly with cerebral arteriosclerosis. It is also used to prevent and treat respiratory infections caused by influenza A virus.

For Parkinson's disease and Parkinson's syndrome, take 100 mg orally, 1 to 2 times a day, and the maximum daily dose is 400 mg. For antiviral treatment, adults take 200 mg once a day or 100 mg once every 12 hours; children aged 1 to 9 years old take 1.5 to 3 mg/kg according to body weight once every 8 hours, or 2.2 to 4.4 mg/kg once every 12 hours; children aged 9 to 12 years old take 100 mg orally every 12 hours; children aged 12 years and above take the same dosage as adults.

Dizziness, insomnia and nervousness, nausea, vomiting, anorexia, dry mouth, constipation. Occasionally, depression, anxiety, hallucinations, mental confusion, ataxia, headache, and rarely, convulsions. Rarely, leukopenia and neutropenia.

People who are allergic to this product.

Precautions for children: It is forbidden to use in newborns and infants under 1 year old. Precautions for pregnancy and lactation: 1. This product can pass through the placenta. Animal experiments have found that when rats are used 50mg/kg daily (12 times the usual dose for humans), it is toxic to the embryo and can cause teratogenesis. Pregnant women should use it with caution. 2. This product can be excreted in breast milk and is forbidden to use in lactating women. Precautions for the elderly: Use with caution.

1. This product combined with ethanol can enhance the central inhibition effect. 2. This product combined with other anti-Parkinson's disease drugs, anticholinergic drugs, antihistamines, phenothiazines or tricyclic antidepressants can enhance the anticholinergic reaction. 3. This product combined with central nervous system stimulants can enhance the excitement of the central nervous system, and in severe cases can cause convulsions or arrhythmias.

Keep away from light and store in sealed container.

0.1g

36 months

Beijing Wanhui Double-Crane Pharmaceutical Company Limited

• Founded in:

  1973-08-01

• Address:

  No. 1 Shangyuan Road, Shilong Economic Development Zone, Mentougou District, Beijing

• Tax NO.:

  91110109101901828X

• Registered Funds:

  83.8626 million yuan

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