Fenbufen Tablets
Function and Efficacy
The product is a long-acting non-steroidal anti-inflammatory drug. After entering the body, it is metabolized into diphenyl ethyl ester, which has the activity of inhibiting cyclooxygenase, reducing the synthesis of prostaglandins and taking effect. Animal experiments show that the anti-inflammatory and analgesic effect of this product is weaker than indomethacin, but stronger than aspirin. Results of acute toxicity test: oral LD50 of rats is 200-720mg/kg, and intraperitoneal LD50 is 265-575mg/kg; oral LD50 of mice is 795-1673mg/kg, and intraperitoneal LD50 is 506-811mg/kg.
Ingredients
The main ingredient of this product is fenbufen. Its chemical name is 3-(4-biphenylcarbonyl) propionic acid. Molecular formula: C16H14O3 Molecular weight: 254.28
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| FenbufenIngredients |
A long-acting nonsteroidal anti-inflammatory drug, after entering the body, it is metabolized into ethyl biphenyl, which inhibits the activity of cyclooxygenase and reduces the synthesis of prostaglandins. Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. More |
36330-85-5 | 9 |
Appearance
This product is white or off-white tablets.
Indication
It is used to treat rheumatoid arthritis, rheumatic arthritis, osteoarthritis, spondyloarthropathies, and gouty arthritis. It can also be used for toothache, postoperative pain, and traumatic pain.
Usage and Dosage
Oral 1. Common adult dosage: 0.6g per day, taken once or twice. The total daily dosage for adults should not exceed 1.0g; 2. Common pediatric dosage: not yet established.
Adverse Reactions
The adverse reactions of this product are mainly gastrointestinal reactions, manifested as stomach pain, burning sensation in the stomach, nausea, and a few serious adverse reactions include gastric ulcer, bleeding, and even perforation. Dizziness, rash, mild decrease in white blood cell count, and mild increase in serum transferase are less common.
Precautions
1. Patients who are allergic to this product are prohibited from using it. 2. Patients with peptic ulcer, severe liver and kidney damage, and aspirin-induced asthma are prohibited from using it.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
0.3g
Manufacturer
Sancai Shiqi Pharmaceutical Co., Ltd.
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Founded in:
2010-12-17 -
Address:
Building B, No. 1 Songbai Road, Torch Development Zone, Zhongshan City -
Tax NO.:
91442000566655786Y -
Registered Funds:
50 million yuan -
Email: