Fenbufen Tablets
Function and Efficacy
1This product is a long-acting non-steroidal anti-inflammatory drug. It can inhibit the activity of cyclooxygenase and reduce the synthesis of prostaglandins. 2Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. 3Acute toxicity test results: The oral LD50 of rats is 200-720mg/kg, and the intraperitoneal injection LD50 is 265-575mg/kg; the oral LD50 of mice is 795-1673mg/kg, and the intraperitoneal injection LD50 is 506-811mg/kg.
Ingredients
The main ingredient of this product is fenbufen (C16H14O3), whose chemical name is 3-(4-biphenylcarbonyl) propionic acid. Its structural formula is: Molecular formula: C16H14O3 Molecular weight: 254.28
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| FenbufenIngredients |
This product is a long-acting non-steroidal anti-inflammatory drug. It can inhibit the activity of cyclooxygenase and reduce the synthesis of prostaglandins. Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. More |
36330-85-5 | 9 |
Appearance
This product is white or off-white tablets.
Indication
It is mainly used for rheumatoid arthritis, rheumatic arthritis, osteoarthritis, gout, ankylosing spondylitis, etc., and can also be used for other painful diseases.
Usage and Dosage
Oral administration: Adults: 0.3g each time, twice a day (three times if necessary) or as directed by a doctor.
Adverse Reactions
The adverse reactions of this product are mainly gastrointestinal reactions, manifested as stomach pain, burning sensation, nausea, and a few serious adverse reactions include gastric ulcer, bleeding, and even perforation. Dizziness, rash, mild decrease in white blood cell count, mild increase in serum transferase, etc. are less common.
Precautions
1. Patients who are allergic to this product are prohibited from using it. 2. Patients with peptic ulcer, severe liver and kidney damage, and aspirin-induced asthma are prohibited from using it.
Special Population Medication
Precautions for children: Do not use. Precautions for pregnancy and lactation: Do not use. Precautions for the elderly: Elderly patients should be aware of renal toxicity due to decreased renal function.
Drug Interactions
There may be cross-allergic reactions with other nonsteroidal anti-inflammatory drugs.
Storage
Keep away from light, sealed and stored in a dry place.
Packaging Specification
0.15g
Validity Period
24 months
Manufacturer
Jiangsu Pingguang Pharmaceutical (Jiaozuo) Co., Ltd.
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Founded in:
2002-03-19 -
Address:
300 meters north of the extension section of Jiefang Avenue, east of Huazhang Road, Fengxian Economic Development Zone -
Tax NO.:
91320321730727420F -
Registered Funds:
14.4522 million yuan -
Email: