Lithium carbonate tablets

This product works in the form of lithium ions. Its mechanism of anti-manic attacks is to inhibit the Ca2-dependent release of norepinephrine and dopamine from nerve endings, promote the reuptake of norepinephrine in the synaptic cleft by nerve cells, increase its conversion and inactivation, thereby reducing the concentration of norepinephrine, and promote the synthesis and release of 5-hydroxytryptamine, which helps stabilize emotions. This product has many adverse reactions, but it is still the first choice for the treatment of mania.

The main ingredient of this product and its chemical name is: lithium carbonate.

This product is white or off-white tablets.

It is mainly used to treat mania, and has a good effect on treating and preventing relapses of bipolar disorder with alternating manic and depressive episodes, and also has a preventive effect on recurrent depression. It is also used to treat schizoaffective psychosis.

The oral dose should be gradually increased and adjusted according to the blood lithium concentration. During the treatment period, the dose is 0.9-1.5 g (3-5 tablets) per day, taken in 1-2 times. For maintenance treatment, the dose is 0.6-0.9 g (2-3 tablets) per day.

Common adverse reactions include dry mouth, thirst, polydipsia, polyuria, constipation, diarrhea, nausea, vomiting, and upper abdominal pain. Adverse reactions of the nervous system include fine tremors in both hands, malaise, weakness, drowsiness, blurred vision, and hyperreflexia of tendons. It can cause an increase in white blood cells. Aggravation of the above adverse reactions may be a precursor to poisoning and should be closely observed.

It is contraindicated in patients with renal insufficiency or severe heart disease.

Precautions for children: Children under 12 years old are prohibited to use. Children over 12 years old should start with a small dose and slowly increase the dose according to the blood lithium concentration. Precautions for pregnancy and lactation: It is prohibited in the first three months of pregnancy. Lactating women should stop breastfeeding while using this product. Precautions for the elderly: Reduce the dosage according to the situation, start with a small dose, slowly increase the dose, and pay close attention to the occurrence of adverse reactions.

1. When this product is used in combination with aminophylline, caffeine or sodium bicarbonate, it can increase the urine excretion of this product, reduce the blood concentration and efficacy. 2. When this product is used in combination with chlorpromazine and other phenothiazine derivatives, the blood concentration of chlorpromazine can be reduced. 3. When this product is used in combination with iodide, it can induce hypothyroidism. 4. When this product is used in combination with norepinephrine, the latter's pressor effect is reduced. 5. When this product is used in combination with muscle relaxants (such as succinylcholine, etc.), the muscle relaxant effect is enhanced and the duration of action is prolonged. 6. When this product is used in combination with piroxicam, it can lead to excessive blood lithium concentration and poisoning.

Keep sealed.

0.25g

24 months