Tobramycin eye drops
Function and Efficacy
1. In vitro experiments show that tobramycin has special effects on the following bacteria: Staphylococci: Staphylococcus aureus, Staphylococcus epidermidis and penicillin-resistant bacteria. Streptococci: Group A hemolytic streptococci, non-hemolytic streptococci and Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis (indole-negative) and indole-positive Proteus, Haemophilus influenzae and Haemophilus conjunctivitis, Moraxella conjunctivitis, Acinetobacter calcoaceticus (Herelle avaginacola), Neisseria. 2. Bacterial sensitivity experiments show that bacteria resistant to gentamicin are still sensitive to tobramycin. No bacteria resistant to tobramycin have been found so far, but long-term use may produce bacterial resistance.
Ingredients
Tobramycin O-3-amino-3-deoxy-α-O-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| TobramycinIngredients |
It has special effects on Staphylococcus (Staphylococcus aureus, Staphylococcus epidermidis and penicillin-resistant strains), Streptococcus (Group A hemolytic streptococci, non-hemolytic streptococci and Streptococcus pneumoniae), Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis (indole-negative and indole-positive), Haemophilus influenzae and Haemophilus conjunctivitis, Moraxella conjunctivitis, Acinetobacter calcoaceticus (Herellea vaginacola), and Neisseria. It is still sensitive to gentamicin-resistant strains, and long-term use may lead to bacterial resistance. More |
32986-56-4 | 13 |
Appearance
This product is a colorless or almost colorless clear solution.
Indication
This product is suitable for local infections of the external eye and its appendages caused by sensitive bacteria.
Usage and Dosage
1. For patients with mild and moderate infections, apply about 1.5 cm of ointment to the affected eye 2 to 3 times a day, and reduce the amount after the condition improves. 2. Tobramycin eye drops can be used in combination with eye ointment, that is, use eye drops during the day and eye ointment at night.
Adverse Reactions
Common adverse reactions are local toxic side effects and allergic reactions in the eye, such as itchy and red eyelids, and conjunctival erythema, with an incidence rate of less than 3%. These adverse reactions can also occur with topical application of other aminoglycoside antibiotics. There are no clinical reports of other adverse reactions to tobramycin. However, if tobramycin ointment is used in combination with systemic aminoglycoside antibiotics, the total drug concentration in the serum should be monitored.
Precautions
1. It is contraindicated for those who are allergic to this product and other aminoglycoside antibiotics; 2. It should be used with caution in pregnant women; 3. It should be used with caution in the elderly; 4. It should be used with caution in children.
Special Population Medication
Precautions for children: Use with caution in children. Precautions for pregnancy and lactation: Use with caution in pregnant women. Precautions for the elderly: Use with caution in the elderly.
Drug Interactions
This experiment has not been conducted and there are no reliable references.
Storage
Keep sealed.
Packaging Specification
5ml:15mg (15,000 units)
Validity Period
24 months
Manufacturer
Jinyao Yongguang (Hebei) Pharmaceutical Co., Ltd.
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Founded in:
1995-12-12 -
Address:
No. 228, Yanchang Road, Yanjiao High-tech Zone, Sanhe City, Hebei Province -
Tax NO.:
91131082601348213C -
Registered Funds:
147.24609159 yuan -
Email: