Piroxicam Capsules
Function and Efficacy
It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. This product has a pharmacological effect by inhibiting cyclooxygenase to reduce the synthesis of local prostaglandins in tissues and inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. The analgesic and detumescent effects of this product in the treatment of arthritis are similar to those of indomethacin, aspirin and naproxen. Acute toxicity test results: The oral LD50 of mice is 360mg/kg.
Ingredients
This product contains piroxicam (C15H13N3O4S) which should be 90.0% to 110.0% of the labeled amount.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| PiroxicamIngredients |
Non-steroidal anti-inflammatory drugs have analgesic, anti-inflammatory and antipyretic effects. They exert their pharmacological effects by inhibiting cyclooxygenase, reducing the synthesis of prostaglandins in local tissues, and inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. More |
36322-90-4 | 33 |
Indication
Used for symptomatic treatment of pain and swelling in various arthritis and soft tissue lesions.
Usage and Dosage
Oral adult dosage: 20 mg once a day, or 10 mg twice a day. Take after meals.
Adverse Reactions
1. Nausea, stomachache, decreased appetite and indigestion are the most common gastrointestinal adverse reactions, of which 3.5% need to withdraw the drug. When the dosage is greater than 20 mg per day, the incidence of gastric ulcer increases significantly, and some are accompanied by bleeding or even perforation. 2. Neutropenia, eosinophilia, increased blood urea nitrogen, dizziness, vertigo, tinnitus, headache, general weakness, edema, rash or itching, etc., with an incidence of 1% to 3%. 3. Abnormal liver function, thrombocytopenia, hyperhidrosis, skin ecchymosis, peeling, erythema multiforme, toxic epithelial necrosis, bullous erythema multiforme (Stevens-Johnson syndrome), skin allergic reaction to light, blurred vision, red and swollen eyes, hypertension, hematuria, hypoglycemia, depression, insomnia and mental tension, etc., with an incidence of 1%.
Precautions
It is contraindicated for patients who are allergic to this product, have peptic ulcers, or chronic gastric diseases.
Drug Interactions
1. When drinking alcohol or taking it with other anti-inflammatory drugs, gastrointestinal adverse reactions increase. 2. When used with anticoagulants such as dicoumarol, the latter's effect is enhanced and the bleeding tendency is significant, so the dosage should be adjusted. 3. When used with aspirin, the blood concentration of this product can drop to 80% of the normal concentration, and the risk of gastrointestinal ulcer formation and bleeding tendency increases.
Storage
Keep away from light and in a dry place.
Packaging Specification
10 mg