Cephalexin and Trimethoprim Capsules
Function and Efficacy
This product inhibits bacterial transpeptidase, prevents the synthesis of bacterial cell walls, and inhibits or kills bacteria. The combination of cephalexin and trimethoprim improves the antibacterial ability, delays the development of drug resistance, and reduces the oral dose.
Ingredients
Each tablet contains 125mg of cephalexin and 25mg of trimethoprim
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CephalexinIngredients |
By inhibiting bacterial transpeptidase, it prevents the synthesis of bacterial cell walls and inhibits or kills bacteria. When used in combination with trimethoprim, it can enhance antibacterial ability, delay the development of drug resistance, and reduce oral dosage. More |
15686-71-2 | 33 | |
| TrimethoprimIngredients |
By inhibiting bacterial transpeptidase, it prevents the synthesis of bacterial cell walls and inhibits or kills bacteria. When used in combination with cephalexin, it can enhance antibacterial ability, delay the development of drug resistance, and reduce oral dosage. More |
738-70-5 | 44 |
Appearance
This product is in the form of capsules.
Indication
Used for infections caused by penicillin-resistant Staphylococci, Streptococci, Pneumococci, Escherichia coli, etc.
Usage and Dosage
It is recommended to be taken orally on an empty stomach. Adults take 1-2 tablets at a time, 4 times a day. Children should take a reduced dosage or follow the doctor's advice.
Adverse Reactions
1. Nausea, vomiting, diarrhea and abdominal discomfort are more common. 2. Allergic reactions such as rash and drug fever are rare, and anaphylactic shock may occur occasionally. 3. Neurological reactions such as dizziness, diplopia, tinnitus, and convulsions. 4. Renal damage may occur occasionally during the use of this product. 5. Occasionally, patients have elevated serum aminotransferases and positive Coombs tests. Hemolytic anemia is rare. Neutropenia and pseudomembranous colitis have also been reported. 6. Trimethoprim's interference with folic acid metabolism can produce adverse reactions in the blood system, such as leukopenia, thrombocytopenia or methemoglobin anemia. Generally, leukopenia and thrombocytopenia are mild, and can be recovered by stopping the drug in time. Folic acid preparations can also be added.
Precautions
1. Patients allergic to cephalosporins or penicillin are prohibited from using this product. 2. Patients allergic to trimethoprim are prohibited from using this product. 3. Neonates and premature infants are prohibited from using this product. 4. Patients with severe liver and kidney diseases are prohibited from using this product. 5. Patients with blood diseases are prohibited from using this product.
Special Population Medication
Precautions for children: It is contraindicated for newborns and premature infants. Precautions for pregnancy and lactation: This product can pass through the placenta and be excreted through breast milk, so pregnant and lactating women should use it with caution. Precautions for the elderly: This product has not been tested and there is no reliable reference literature.
Drug Interactions
1. When used in combination with cholestyramine (cholestyramine), the average blood concentration of cephalexin can be reduced. 2. Probenecid can delay the renal excretion of this product, and there are also reports that probenecid can increase the excretion of this product in bile. 3. The chance of leukopenia and thrombocytopenia increases when bone marrow suppressants are used in combination with this product. 4. This product should not be used simultaneously with anti-tumor drugs 2,4-diaminopyrimidines, nor should it be used between courses of treatment with other folic acid antagonists, because it may cause bone marrow aplasia or megaloblastic anemia. 5. Co-use with cyclosporine may increase renal toxicity.
Storage
Keep in a dark, sealed and cool place
Packaging Specification
Each tablet contains 0.125g of cephalexin and 0.025g of trimethoprim
Validity Period
Tentative 24 months
Manufacturer
Tonghua Zhengyuan Pharmaceutical Co., Ltd.
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Founded in:
2015-09-25 -
Address:
No. 111, Jingkai Ring Road, Tonghua City -
Tax NO.:
91220505340063729F -
Registered Funds:
570 million yuan -
Email: