Fosfomycin calcium tablets
Function and Efficacy
This product is a broad-spectrum antibiotic. It inhibits the early synthesis of bacterial cell walls, which leads to the death of bacteria. This product has a wide antibacterial spectrum and has a certain antibacterial effect on most Gram-positive and Gram-negative bacteria. The antibacterial spectrum of this product includes Staphylococcus aureus, Escherichia coli, Shigella, Serratia, Shigella, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterobacter aerogenes.
Ingredients
The main ingredient of this product is fosfomycin calcium. Chemical name: (-)-(1R, 2S)-(1,2-epoxypropyl)-calcium phosphate-hydrate. Chemical structure: Molecular formula: C3H5O4CaP·H2O Molecular weight: 194.14
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Fosfomycin calciumIngredients |
By inhibiting the early synthesis of bacterial cell walls, the cell wall synthesis of bacteria is inhibited, leading to their death. It has a certain antibacterial effect on most Gram-positive and Gram-negative bacteria, and the antibacterial spectrum includes Staphylococcus aureus, Escherichia coli, Shigella, Serratia, Shigella, Pseudomonas aeruginosa, Klebsiella pneumoniae and Enterobacter aerogenes. More |
26472-47-9 | 5 |
Appearance
This product is white or off-white tablets.
Indication
Oral administration is suitable for the following infections caused by pathogens sensitive to fosfomycin: 1. Intestinal infections: bacterial enteritis, bacillary dysentery. 2. Urinary tract infections: cystitis, pyelonephritis, urethritis. 3. Dermatological and soft tissue infections: furunculosis, anthrax, sweat gland inflammation, lymphadenitis, folliculitis. 4. Respiratory tract infections: nasopharyngitis, tonsillitis, tracheitis, early chronic bronchitis. 5. Ophthalmology: sty, dacryocystitis. 6. Gynecology: vaginitis, cervicitis.
Usage and Dosage
For oral administration, adults take 2-4 g of fosfomycin acid per day; children take 50-100 mg/kg per day based on body weight, divided into 3-4 doses.
Adverse Reactions
Mainly mild gastrointestinal reactions, such as nausea, decreased appetite, upper abdominal discomfort, loose stools or mild diarrhea, etc. Generally, it does not affect the continued use of the drug. Occasionally, skin rash, eosinophilia, and elevated alanine aminotransferase may occur. No toxic reactions to the kidneys or blood system were observed.
Precautions
Not yet clear.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution for pregnant women. Precautions for the elderly: Not yet clear.
Drug Interactions
1. It has a synergistic effect when used in combination with beta-lactams against Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus) and Pseudomonas aeruginosa. 2. It has a synergistic effect when used in combination with aminoglycosides. 3. There is no cross-resistance with other antibiotics.
Storage
Sealed and stored in a dry place. Valid for two years
Packaging Specification
0.5g (calculated as C3H704P)
Validity Period
24 months
Manufacturer
NORTHEAST Pharmaceutical Group Shenyang NO.1 Pharmaceutical Co., Ltd.
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Founded in:
1989-01-25 -
Address:
No. 8 Kunming Lake Street, Shenyang Economic and Technological Development Zone -
Tax NO.:
91210106242656694M -
Registered Funds:
80 million yuan -
Website:
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Email: