Tianeptine Sodium Tablets

Tianeptine is an antidepressant. It has the following characteristics of action on animals: increasing the spontaneous activity of pyramidal cells in the hippocampus, accelerating the recovery after functional inhibition, and accelerating the rate of 5-hydroxytryptamine uptake by neurons in the cerebral cortex and hippocampus. Tianeptine has the following characteristics of action on humans: its effect on mood disorders is between the two categories of sedative and excitatory antidepressants. It has a significant effect on physical discomfort symptoms, especially gastrointestinal discomfort symptoms related to anxiety and mood disorders. It has a relieving effect on personality and behavioral abnormalities in alcohol-dependent patients during the withdrawal process.

The main ingredient is tianeptine (sodium salt). The molecular formula is C21H24CIN2NaO4S. The weight is 458.9.

This medicine is a white film-coated tablet.

It is recommended for the treatment of mild, moderate or severe depression, neurogenic and reactive depression, anxiety and depression caused by physical discomfort, especially gastrointestinal discomfort, and anxiety and depression in alcohol-dependent patients during withdrawal.

The recommended dose is 12.5 mg/time, taken orally 3 times a day before the main meals in the morning, afternoon and evening. Chronic alcoholics, regardless of whether they have liver cirrhosis, do not need to adjust the dose. For patients over 70 years old and with renal insufficiency, the dose is limited to 2 tablets per day. Stop treatment and monitor closely, immediately perform gastric lavage, perform cardiopulmonary, metabolic and renal function monitoring, and treat symptomatically for possible abnormalities, paying special attention to ventilation, and correcting metabolic and renal function abnormalities.

Rare, usually mild upper abdominal discomfort, abdominal pain, dry mouth, anorexia, nausea, vomiting, constipation, bloating; insomnia, drowsiness, nightmares, weakness; tachycardia, premature contractions, pain behind the sternum; dizziness, headache, syncope, tremor, fever and flushing; dyspnea, itchy throat; myalgia, back pain.

Not for use by children under 15 years old.

Precautions for children: See [Contraindications] Precautions for pregnancy and lactation: Pregnancy - In animals, studies have found that this drug has no adverse effects on reproductive function, only a very small amount of the drug passes through the placenta, and no accumulation in the fetus is observed. - Because there is no relevant clinical research data in humans, the possible dangers are not yet known, so avoid taking this drug during pregnancy. Tricyclic antidepressants can be secreted into breast milk during lactation, so it is recommended that lactating women not use it. Precautions for the elderly: See [Usage and Dosage]

Avoid co-administration with non-selective MAOIs because of the risk of shock or paroxysmal hypertension, hyperthermia, convulsions, and death. Patients using MAOIs must stop taking them for 2 weeks before taking tianeptine; MAOIs can be used 24 hours after stopping tianeptine. Salicylic acid can reduce the protein binding rate of this drug, so it is recommended to reduce the dosage of this drug when taking high doses of salicylic acid at the same time.

Store below 30℃.

12.5 mg

36 months