Puerarin for injection

This product is a flavonoid glycoside extracted from the root of Pueraria lobata or Pueraria lobata in the Leguminosae family. Animal experiments show that: 1. Effect on smooth muscle: Various total flavonoid compounds in Pueraria lobata have the effect of relaxing smooth muscle, while the contractile components may be substances such as choline, acetylcholine and carceline R. 2. Effect on body temperature: After artificial fever was caused by intravenous injection of expired typhoid vaccine into rabbit ears, the body temperature decreased after oral administration of 20% Pueraria lobata decoction or 20% ethanol infusion, and the effect of the infusion was particularly obvious. 3. Effect on the cardiovascular system: Pueraria lobata has a certain antihypertensive effect on normal and hypertensive animals. Pueraria lobata total flavonoids and puerarin have a significant effect of dilating coronary arteries, which can dilate normal and spasmodic coronary arteries. After intravenous injection of 30mg/Kg, coronary blood flow can increase by 40% and vascular resistance can decrease by 29%. Puerarin can also inhibit the release of 5-HT in platelets induced by thrombin.

8-β-D-Glucopyranose-4',7-dihydroxyisoflavone

This product is a colorless or light yellow clear liquid. The solution prepared with 50% propylene glycol is slightly viscous.

It can be used as an auxiliary treatment for coronary heart disease, angina pectoris, myocardial infarction, retinal artery and vein occlusion, sudden deafness and ischemic cerebrovascular disease, viral myocarditis in children, diabetes, etc.

Intravenous drip: 200-400 mg each time, added to 500 ml of glucose solution and dripped, once a day, 10-20 days as a course of treatment, can be used continuously for 2-3 courses.

1. A small number of patients experience temporary abdominal distension, nausea and other reactions at the beginning of medication, which can disappear on their own with continued medication. 2. A very small number of patients experience allergic reactions such as rash and fever after medication, which can return to normal after immediate discontinuation of medication or symptomatic treatment.

1. Patients with severe liver and kidney damage, heart failure and other serious organic diseases are prohibited from using this product. 2. Patients with bleeding tendency should use this product with caution.

Precautions for children: Although puerarin has the characteristics of rapid absorption, distribution and clearance in the body, it should be used with caution in the case of reduced doses, taking into account the physiological characteristics of children. Precautions for pregnancy and lactation: Pregnant women should use it with caution when it has not been verified whether puerarin is toxic to the fetus. Because puerarin is widely distributed in tissues, it is not recommended to use it during lactation when it is not clear whether puerarin can be excreted through breast milk. Precautions for the elderly: For patients with normal liver and kidney function, this product is suitable for elderly patients; considering the decline in renal function in elderly patients, it should be used under the supervision of a doctor.

It is not clear yet. However, no clear adverse reactions have been observed when used in combination with currently commonly used cardiovascular drugs.

Keep away from light and store in a sealed container.

0.2g

18 months

North China Pharmaceutical Company.Ltd

• Founded in:

  1992-12-20

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  No. 388, Heping East Road, Shijiazhuang City

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  91130100104397700P

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