Bifendate dripping pills

This product is an enzyme-lowering drug for the treatment of hepatitis created in my country. It is an intermediate in the synthesis of Schisandra chinensis C. Oral administration of 150~200 mg/kg of this product to mice can reduce liver damage caused by carbon tetrachloride and the increase of alanine aminotransferase (ALT). It has an inhibitory effect on liver microsomal lipid peroxidation caused by carbon tetrachloride and the conversion of carbon tetrachloride into carbon monoxide, and reduces the consumption of reduced coenzyme II and oxygen in the process of carbon tetrachloride metabolism, thereby protecting the structure and function of liver cell biomembrane. This product can also reduce the increase of liver ALT induced by prednisone and promote liver regeneration in mice with partial hepatectomy. The enzyme-lowering effect of this product does not directly inhibit the activity of serum and liver ALT, nor does it accelerate the inactivation of ALT in the blood. It may be a reflection of the reduction of liver tissue damage. This product has a significant induction effect on the activity of cytochrome P450 enzymes, thereby enhancing the detoxification ability of carbon tetrachloride and certain carcinogens. It has an effect on improving protein metabolism in some hepatitis patients, increasing albumin and reducing globulin. It has no effect on negative conversion of HbsAg and HbeAg, and cannot shrink enlarged liver and spleen.

The main ingredients of this product and their chemical names: The main ingredient of this product is biphenyl diester drop pills, and its chemical name is 4,4-dimethoxy-5,6,5',6'-bis(methylenedioxy)biphenyl-2,2'-dicarboxylic acid dimethyl ester.

Bifendate is a white crystalline powder, almost soluble in water, very slightly soluble in methanol or ethanol, slightly soluble in acetone, and easily soluble in chloroform or dimethylformamide. This product is a sugar-coated pill.

It is clinically used for patients with chronic persistent hepatitis accompanied by elevated ALT, and can also be used for elevated ALT caused by chemical poisons and drugs.

Oral administration: Drop pills, 5 pills/time, 3 times a day, 6-10 pills/time, 3 times a day if necessary, for 3 months, after ALT returns to normal, change to 5 pills/time, 3 times a day, for 3 months. Oral administration for children: 0.5 mg/kg, 3 times a day, for 3-6 months.

In some cases, dry mouth, mild nausea and occasional rash may occur, which usually disappear after taking anti-allergic drugs.

Patients with cirrhosis of the liver should not use this product. Patients with chronic active hepatitis should use it with caution.

Precautions for children: Reduce the dosage for children. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: Elderly patients should use this product with caution.

The combined use of inosine can reduce the enzyme-lowering rebound phenomenon of this product.

Keep away from light and store in airtight container.

1.5mg

36 months

Wanbangde Pharmaceutical Group Co., Ltd.

• Founded in:

  2002-07-29

• Address:

  No. 28, Baizhang North Road, Chengdong Street, Wenling City, Taizhou City, Zhejiang Province

• Tax NO.:

  9133100074290886X3

• Registered Funds:

  360 million yuan

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