Cefuroxime for injection

This product is a first-generation cephalosporin, which has good antibacterial effect on some strains of Gram-positive cocci such as non-penicillinase-producing and penicillinase-producing Staphylococcus aureus, coagulase-negative Staphylococci, group A hemolytic streptococci, Streptococcus pneumoniae and viridans streptococci. Anaerobic Gram-positive bacteria are mostly sensitive to this product, while Bacteroides fragilis is resistant to it. Methicillin-resistant Staphylococci and Enterococci are resistant to this product. The effect of this product on Gram-positive and Gram-negative bacteria is similar to that of cephalexin. This product has a certain effect on gonococci and is also active against enzyme-producing gonococci; its activity against Haemophilus influenzae is poor.

The main ingredient of this product is cefradine

This product is a sterile powder made of cefuroxime plus an appropriate amount of solvent, and is white or off-white in color.

It is suitable for respiratory tract infections such as acute pharyngitis, tonsillitis, otitis media, bronchitis and pneumonia, urinary and reproductive tract infections, and skin and soft tissue infections caused by sensitive bacteria.

Intravenous drip, intravenous injection or intramuscular injection. Adults: 0.5-1.0g once, once every 6 hours, the maximum daily dose is 8g. Children: (over 1 year old) 12.5-25mg/kg once according to body weight, once every 6 hours. When preparing intramuscular injection, add 0.5g to 2ml of injection water in a bottle and inject deeply into the muscle. When preparing intravenous injection solution, add 6-10ml of injection water or 5% glucose injection solution into the bottle.

The adverse reactions of this product are mild and the incidence is low, about 6%. Gastrointestinal reactions such as nausea, vomiting, diarrhea, and upper abdominal discomfort are more common. The incidence of drug rash is about 1% to 3%. Pseudomembranous colitis, eosinophilia, positive reaction to direct Coombs test, peripheral blood leukocytopenia and neutrophil granulocyte reduction are seen in individual patients. A small number of patients may experience temporary increase in blood urea nitrogen, transient increase in serum aminotransferase and serum alkaline phosphatase. This product is painful when injected intramuscularly, and there are reports of phlebitis after intravenous injection.

This product is contraindicated in patients who are allergic to cephalosporins or have a history of anaphylactic shock or immediate reaction to penicillin.

1. This product and aminoglycoside antibiotics can inactivate each other. When the above drugs are given at the same time, they should be administered at different sites and the two types of drugs should not be mixed in the same container. 2. This product cannot be mixed with other antibiotics. 3. The combination of furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other anti-tumor drugs, as well as glycopeptides and aminoglycoside antibiotics with this product may increase nephrotoxicity. 4. Probenecid can delay the renal excretion of this product. 5. This product contains sodium carbonate, so it is contraindicated with calcium-containing solutions such as compound sodium chloride injection.

Keep tightly closed in a cool, dark place.

Calculated as C16H19N3O4S 1.0g

Shandong Lukang Pharmaceutical Co., Ltd.

• Founded in:

  1993-02-15

• Address:

  No. 88, Deyuan Road, Jining High-tech Zone, Shandong Province

• Tax NO.:

  913700001659297311

• Registered Funds:

  880.229735 yuan

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