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Dexamethasone Sodium Phosphate Injection

Ingredients

The main ingredient of this product is dexamethasone sodium phosphate. Its chemical name is: 16α-methyl-11β,17α,21-trihydroxy-9α-fluoropregnane-1,4-diene-3,20-dione-21-phosphate disodium salt.

Name Description Content CAS NO. Manufacturer
Dexamethasone sodium phosphateIngredients

55203-24-2 24

Indication

It is mainly used for allergic and autoimmune inflammatory diseases. It is mostly used for connective tissue diseases, active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, ulcerative colitis, acute leukemia, etc. It is also used for the comprehensive treatment of certain severe infections and poisonings, and malignant lymphomas.

Usage and Dosage

Intravenous injection

Adverse Reactions

There are no obvious adverse reactions when glucocorticoids are used for replacement therapy at physiological doses. Adverse reactions mostly occur when pharmacological doses are used, and are closely related to the course of treatment, dose, type of medication, usage and route of administration. Common adverse reactions are as follows: 1. Long-term use may cause the following side effects: iatrogenic Cushing's syndrome facial and body shape, weight gain, lower limb edema, purple lines, easy bleeding tendency, poor wound healing, acne, menstrual disorders, avascular necrosis of the humeral or femoral head, osteoporosis and fractures (including vertebral compression fractures, long bone pathological fractures). For more details, please refer to the instructions.

Precautions

Patients with a history of allergy to this product and adrenal cortical hormones are contraindicated to use this product. It should be used in special circumstances after weighing the pros and cons and paying attention to the possibility of worsening of the condition: patients with hypertension, thrombosis, gastric and duodenal ulcers, mental illness, abnormal electrolyte metabolism, myocardial infarction, visceral surgery, glaucoma, etc. are generally not suitable for use.

Special Population Medication

Precautions during pregnancy and lactation: Pregnant women may increase the incidence of placental insufficiency, neonatal weight loss or stillbirth. Animal tests have teratogenic effects, so the pros and cons should be weighed before use. Breastfeeding mothers who receive large doses should not breastfeed to prevent the drug from being excreted through breast milk, causing adverse reactions such as infant growth inhibition and adrenal function inhibition. Precautions for the elderly: It is easy to develop hypertension and diabetes. Elderly patients, especially postmenopausal women, may aggravate osteoporosis when using it.

Drug Interactions

1. When taken with barbiturates, phenytoin, and rifampicin, the metabolic promoting effect of this product is weakened. 2. When used with salicylic acid drugs, their toxicity is increased. 3. It can weaken the effects of anticoagulants and oral hypoglycemic drugs, and the dosage should be adjusted.

Storage

normal temperature

Packaging Specification

1ml:2mg*10pcs/box

Manufacturer

Kaifeng Pharmaceutical (GROUP) Co., Ltd.

  • Founded in:

    2003-09-26
  • Address:

    No. 1, Yunan Street, Kaifeng City
  • Tax NO.:

    914102007551588773
  • Registered Funds:

    204.568562 million yuan
  • Email:

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