Compound acetaminophen tablets
Function and Efficacy
This product is an acetanilide antipyretic analgesic. It inhibits cyclooxygenase and selectively inhibits the synthesis of prostaglandins in the hypothalamic temperature regulation center, leading to peripheral vasodilation and sweating to achieve an antipyretic effect. Its antipyretic effect is similar to that of aspirin. It inhibits the synthesis and release of prostaglandins, etc., increases the pain threshold and has an analgesic effect. It is a peripheral analgesic, weaker than aspirin, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect.
Ingredients
This product is a compound preparation. Each tablet contains the main ingredients of 126 mg of acetaminophen, 230 mg of aspirin, and 30 mg of caffeine.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AcetaminophenIngredients |
By inhibiting cyclooxygenase, it selectively inhibits the synthesis of prostaglandins in the hypothalamic temperature regulation center, leading to peripheral vasodilation and sweating to achieve an antipyretic effect; by inhibiting the synthesis and release of prostaglandins, it increases the pain threshold and has an analgesic effect. It is a peripheral analgesic, weaker than aspirin, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect. More |
103-90-2 | 68 | |
| Acetylsalicylic acidIngredients |
By inhibiting cyclooxygenase, it selectively inhibits the synthesis of prostaglandins in the hypothalamic temperature regulation center, leading to peripheral vasodilation and sweating to achieve the effect of antipyretic; by inhibiting the synthesis and release of prostaglandins, it increases the pain threshold and plays an analgesic role. It is a peripheral analgesic, with a stronger effect than acetaminophen, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect. More |
50-78-2 | 35 |
Appearance
This product is white flakes with a slightly sour and bitter taste and easily deteriorates when exposed to moisture.
Indication
Usage and Dosage
Oral administration, 1 tablet at a time for adults. If fever or pain persists, the medication can be repeated every 4-6 hours, not more than 4 times within 24 hours.
Adverse Reactions
At conventional doses, acetaminophen has few adverse reactions, and may occasionally cause nausea, vomiting, sweating, abdominal pain, pale skin, etc. In a few cases, allergic dermatitis (rash, skin itching, etc.), granulocytopenia, thrombocytopenia, methemoglobinemia, anemia, liver and kidney damage, etc. may occur. It rarely causes gastrointestinal bleeding.
Precautions
It is contraindicated for patients with severe hepatic and renal impairment and those who are allergic to this product.
Drug Interactions
(1) Long-term drinking or use of other liver enzyme inducers, especially barbiturates or anticonvulsants, are more likely to cause liver toxicity when taking this product for a long time or in large quantities. (2) When this product is used in combination with chloramphenicol, it can prolong the half-life of the latter and enhance its toxicity. (3) When used in combination with anticoagulants, it can enhance the anticoagulant effect, so the dosage of anticoagulants should be adjusted. (4) When used in combination with aspirin or other non-steroidal anti-inflammatory drugs for a long time and in large quantities, there is a significant increase in the risk of renal toxicity. (5) When this product is used in combination with the antiviral drug zidovudine, its toxicity can be increased, so simultaneous use should be avoided.
Storage
Sealed, store in a dry place.
Packaging Specification
Compound