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Nimesulide Dispersible Tablets

Function and Efficacy

This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.

Ingredients

The main ingredient of this product is nimesulide, and its chemical name is: N-[4-nitro-2-phenoxyphenyl] methanesulfonamide.

Name Description Content CAS NO. Manufacturer
NimesulideIngredients

This product is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is not yet fully understood, but it may be mainly related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.

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51803-78-2 14

Appearance

This product is off-white to light yellow irregular tablets.

Indication

This product is a non-steroidal anti-inflammatory drug and is only used when at least one other non-steroidal anti-inflammatory drug has failed. It can be used for the pain of chronic arthritis (such as osteoarthritis), pain after surgery and acute trauma, and symptomatic treatment of primary dysmenorrhea.

Usage and Dosage

Oral administration: 0.05-0.1g at a time, twice a day, after meals. The maximum single dose should not exceed 100mg, and the course of treatment should not exceed 15 days. It is recommended to use the minimum effective dose and the shortest course of treatment to reduce the occurrence of adverse drug reactions.

Adverse Reactions

The main symptoms are heartburn, nausea, and stomach pain, but the symptoms are mild and short-lived, and rarely require discontinuation of treatment. Allergic rashes may occur in rare cases. Dizziness, drowsiness, gastric ulcers or gastrointestinal bleeding, and Stevens-Johnson syndrome may also occur.

Precautions

1. Patients who are allergic to this product, acetylsalicylic acid or other non-steroidal drugs are contraindicated. 2. Patients with active gastrointestinal bleeding or active peptic ulcer are contraindicated. 3. Patients with severe liver dysfunction and severe renal dysfunction (creatinine clearance rate 30 ml/min) are contraindicated.

Special Population Medication

Precautions for children: Children under 12 years old are prohibited from using this medicine. Precautions for pregnancy and lactation: There are no tests to prove whether nimesulide is toxic to the fetus, so it is not recommended for pregnant women. It has not been confirmed whether nimesulide is excreted through breast milk, so it is not recommended for lactating women. Precautions for the elderly: Due to the decline in renal function in elderly patients, the dosage can be appropriately reduced according to the situation.

Drug Interactions

This product has a high plasma protein binding rate and may displace other protein-bound drugs.

Storage

Seal and store in a dry place. The validity period is tentatively one year.

Packaging Specification

0.1g

Validity Period

Tentatively two years.

Manufacturer

Hubei Shubang Pharmaceutical Co., Ltd.

  • Founded in:

    2012-04-17
  • Address:

    No. 1 Sibao Road, Xiantao City
  • Tax NO.:

    914290045942134679
  • Registered Funds:

    48 million yuan
  • Email:

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