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Cefdizime Sodium for Injection

Function and Efficacy

This product belongs to the third generation of cephalosporin, with a broad-spectrum antibacterial effect, and is stable to β-lactamase produced by most bacteria. This product is mainly effective against a variety of G and G- bacteria and anaerobic bacteria. It has an immunomodulatory effect, that is, it can be used as a biological response modifier (BRM) to increase CD4 in the body, thereby increasing the CD4/CD8 value and playing a synergistic bactericidal effect. This product is ineffective against Bacteroides, Acinetobacter, Enterococcus faecalis, Listeria, Mycoplasma, and Chlamydia. The mechanism of action of this product is that this product achieves a bactericidal effect by inhibiting the biosynthesis of bacterial cell wall mucopeptides.

Ingredients

Cefdizime Sodium

Name Description Content CAS NO. Manufacturer
CefodizimeIngredients

This product belongs to the third generation of cephalosporin, has a broad-spectrum antibacterial effect, and is stable to β-lactamase produced by most bacteria. This product is mainly effective against a variety of G and G- bacteria and anaerobic bacteria. It has an immunomodulatory effect, that is, it can be used as a biological response modifier (BRM) to increase CD4 in the body, thereby increasing the CD4/CD8 value and playing a synergistic bactericidal effect. The mechanism of action of this product is that this product achieves a bactericidal effect by inhibiting the biosynthesis of bacterial cell wall mucopeptides.

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69739-16-8 1

Appearance

This product is white to light yellow crystalline powder.

Indication

Used for infections caused by sensitive bacteria, such as upper and lower urinary tract infections, lower respiratory tract infections, gonorrhea, etc.

Usage and Dosage

Intravenous injection: 1.0g of this product is dissolved in 4ml water for injection, or 2.0g is dissolved in 10ml water for injection, and injected within 3 to 5 minutes. Intravenous infusion: 1.0g or 2.0g of this product is dissolved in 40ml water for injection, saline or Ringer's solution, and infused within 20 to 30 minutes. Intramuscular injection: 1.0g of this product is dissolved in 4ml water for injection or 2.0g is dissolved in 10ml water for injection, and injected deep into the gluteal muscle; to prevent pain, this product can be dissolved in 1% lidocaine solution and injected (at this time, injection into the blood vessel must be avoided).

Adverse Reactions

Occasionally, there are symptoms of diarrhea, rash, urticaria, itching or fever, nausea and vomiting, abdominal pain or anorexia. Occasionally, there are fever, cough, dyspnea, anemia, granulocytopenia, thrombocytopenia, and eosinophilia. Shock is extremely rare and should be administered with caution. If it occurs, the drug should be discontinued and appropriate treatment should be given.

Precautions

It is contraindicated in patients allergic to cephalosporins.

Drug Interactions

Probenecid can delay the excretion of this product. This product can enhance the toxic effects of potentially nephrotoxic drugs. If it is used simultaneously or sequentially with aminoglycosides, amphotericin B, cyclosporine, cisplatin, vancomycin, polymyxin B or colistin, renal function should be closely monitored.

Storage

Keep in a dark place, sealed and stored below 25℃. Validity period: 18 months

Packaging Specification

0.25g (calculated as C20H20N6O7S4)

Manufacturer

Shantou Jinshi Sterilize Powder For Injection Co., Ltd.

  • Founded in:

    1994-04-29
  • Address:

    No. 36, Taishan Road, Shantou City
  • Tax NO.:

    914405002798080307
  • Registered Funds:

    17 million yuan
  • Website:

  • Email:

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